Frantz's tumor of the pancreas

BACKGROUND: The solid-cystic tumor of the pancreas is rare, and had several names, including "papillary cystic tumor," "solid cystic tumor," "solid and papillary epithelial neoplasm." About 90% of cases are found in young women, measuring between seven and 20 cm in diameter, with 40% of them in the head, tail 32% and 28% in the body. CASE REPORT: Woman of 29 years was admitted for investigation of strong and persistent pain in right hypochondrium. It was performed ultrasonography and abdominal computed tomography, showing lobulated mass with the consistency of soft parts in the tail of the pancreas, peripheral capsular enhancement and hypovascular center measuring 5.5x5,5x5,0 cm. MRI better defined, with intermediate signal on T1 and T2, small scattered foci of low signal on T2 and peripheral enhancement by gadolinium, suggesting tumor Frantz. She underwent parcial pancreatectomy and total splenectomy. Macroscopic and microscopic findings suggested, and immunohistochemistry confirmed the diagnosis. CONCLUSION: Should be considered this tumor in the differential diagnosis of abdominal masses in young women.

Pseudopapillary Solid Cystic Tumor Arising From an Extrapancreatic Site

A case of pseudopapillary solid cystic tumor arising in the omentum of a 46-year-old woman is presented. A well-defined, encapsulated tumor measuring 5.2 × 4.0 × 4.0 cm was histologically characterized by a combination of solid and pseudopapillary growth patterns of tumor cells with abundant pale-to-eosinophilic cytoplasm. No pancreatic tissue was observed within or adjacent to the tumor. Immunohistochemically, the tumor was positive for vimentin, epithelial membrane antigen, and α1-antichymotrypsin. Ultrastructurally, the tumor cells contained electron dense granules of variable sizes, most likely representing lysosomes. Flow cytometry showed a diploid DNA content with a high S-phase fraction. The patient was well without recurrence 3 months after diagnosis. It is important to include pseudopapillary solid cystic tumor in the differential diagnosis of omental tumors.