Isolated Cleft of the Posterior Mitral Leaflet in 8 Year Old Patient

Cleft of the mitral valve is a rare cause of the congenital mitral regurgitation. Isolated cleft is uncommon finding and is more often found associated with some form of endocardial cushion defect. Cleft of the septal leaflet is found much more often than the defect in the posterior leaflet. Mitral clefts can extend to the mitral annulus or they can be less ''deep'' and show only minor regurgitation. Clinical importance of the isolated cleft of the mitral valve (ICMV) is that it can be successfully corrected by surgery and that it can have good long-term results.

Diagnosis of Isolated Cleft of the Anterior Mitral Leaflet in a Dog: A Case Study Using Real-Time Three-Dimensional Echocardiography

Isolated cleft of the anterior mitral leaflet (ICAML) in dogs without a septal defect is a rare pathological condition. Until now, only one paper has contributed to the detailed understanding of canine ICAML. Reports have confirmed that 3-dimensional echocardiography (3-DE) is a simple and fast imaging technique that is useful for the diagnosis of ICAML and morphological evaluation of the mitral valve in humans. However, to our knowledge, no studies have provided details about the effectiveness of 3-DE in ICAML diagnosis in dogs. Thus, we aimed to determine the usefulness of a diagnostic technique using 3-DE in a 2-year-old Cavalier King Charles Spaniel with ICAML that exhibited mild mitral valve regurgitation. ICAML was initially assessed by transthoracic two-dimensional echocardiography. A diagnosis of congenital mitral regurgitation due to ICAML and understanding of the morphological structure of the valve was established based on the 3-DE findings.

Isolated cleft of the posterior mitral valve leaflet with mitral valve prolapse

Isolated cleft of posterior mitral valve leaflet is a very rare cause of congenital mitral regurgitation. We present a 56-year-old woman referred for an echocardiogram by her physician for evaluation of a cardiac murmur. The echocardiogram showed normal left ventricular sizes and function; an isolated cleft of the posterior mitral valve leaflet with posterior leaflet prolapse causing severe mitral regurgitation. The patient was treated surgically with excellent outcome.

Congenital mitral regurgitation with Down syndrome

A 19-year-old man with Down syndrome had congenital mitral regurgitation. He had slight mental retardation and difficulty in performing independent oral drug administration. We planned mitral valve plasty to avoid postoperative anticoagulant therapy. The mitral valve lesions were complicated. A prolapsed anterior mitral leaflet, shortened posterior leaflet, abnormal cleft, abnormal papillary muscle, and enlarged annulus were observed. Successful mitral valve plasty was performed using several techniques. The postoperative course was uneventful, and no significant mitral regurgitation was found.

Rare Combination of Pathologies Causing Mitral Stenosis and Mitral Regurgitation: A Case Report

A supramitral ring is a rare cause of mitral stenosis, while an isolated mitral valve cleft is a rare cause of congenital mitral regurgitation. Fortunately, both the lesions are known to have good outcomes after surgical correction. Although each is known to be associated with a variety of other structural heart defects, their coexistence has not been reported previously. We report a case of a three- and half-year-old boy detected to have a rare combination of supramitral ring producing severe mitral stenosis with a coexisting cleft in the anterior leaflet of mitral valve causing severe mitral regurgitation. The patient underwent successful surgical repair with resolution of both mitral stenosis and regurgitation.