Familial Presentation of Intracranial Occlusive Arteriopathy and Ischemic Stroke in Patients with Graves’ Hyperthyroidism

Background:The comorbidity of intracranial occlusive arteriopathy and Graves’ disease (GD) is increasingly being reported.Methods:We describe two patients (mother and daughter) with GD, intracranial occlusive arteriopathy, and ischemic strokes.Results:Both patients were thyrotoxic at the time of the ischemic event, and the intracranial arterial stenosis was progressive while in thyrotoxic state. In one of the cases, there was no further progression of the disease after 1 year of follow up, once hyperthyroidism was well controlled.Conclusion:To the best of our knowledge, this is the first report of familial presentation of moyamoya-like vasculopathy in patients with GD in Latin population.

Digitale Durchblutungsstörungen und Parvovirus B19 Infektion

We report a case of a 37-year-old white woman, who presented with digital arterial occlusions associated with parvovirus B19 infection. Two other member of the family presented acute febrile illness, polyarthralgia (husband), and erythema infectiosum (son) during the same month. This new report gives weight to the concept that acute human parvovirus infection could become part of the differential diagnosis of acute digital occlusive arteriopathy.