Study of footprint variations of CCP considering machine kinematics

This paper investigates the differentiation between machine’s static and dynamic footprint (FP). The results have shown progressing footprint variation related to tool’s tilt angle. Continuous tilt angle compensation has been applied to offset this effect.

Dynamic footprint of sequestration in the molecular fluctuations of osteopontin

The sequestration of calcium phosphate by unfolded proteins is fundamental to the stabilization of biofluids supersaturated with respect to hydroxyapatite, such as milk, blood or urine. The unfolded state of osteopontin (OPN) is thought to be a prerequisite for this activity, which leads to the formation of core–shell calcium phosphate nanoclusters. We report on the structures and dynamics of a native OPN peptide from bovine milk, studied by neutron spectroscopy and small-angle X-ray and neutron scattering. The effects of sequestration are quantified on the nanosecond– ångström resolution by elastic incoherent neutron scattering. The molecular fluctuations of the free phosphopeptide are in agreement with a highly flexible protein. An increased resilience to diffusive motions of OPN is corroborated by molecular fluctuations similar to those observed for globular proteins, yet retaining conformational flexibilities. The results bring insight into the modulation of the activity of OPN and phosphopeptides with a role in the control of biomineralization. The quantification of such effects provides an important handle for the future design of new peptides based on the dynamics–activity relationship.

Dynamic Footprint Measurement Collection Technique and Intrarater Reliability

Background: Identifying the variability of footprint measurement collection techniques and the reliability of footprint measurements would assist with appropriate clinical foot posture appraisal. We sought to identify relationships between these measures in a healthy population. Methods: On 30 healthy participants, midgait dynamic footprint measurements were collected using an ink mat, paper pedography, and electronic pedography. The footprints were then digitized, and the following footprint indices were calculated with photo digital planimetry software: footprint index, arch index, truncated arch index, Chippaux-Smirak Index, and Staheli Index. Differences between techniques were identified with repeated-measures analysis of variance with post hoc test of Scheffe. In addition, to assess practical similarities between the different methods, intraclass correlation coefficients (ICCs) were calculated. To assess intrarater reliability, footprint indices were calculated twice on 10 randomly selected ink mat footprint measurements, and the ICC was calculated. Results: Dynamic footprint measurements collected with an ink mat significantly differed from those collected with paper pedography (ICC, 0.85–0.96) and electronic pedography (ICC, 0.29–0.79), regardless of the practical similarities noted with ICC values (P = .00). Intrarater reliability for dynamic ink mat footprint measurements was high for the footprint index, arch index, truncated arch index, Chippaux-Smirak Index, and Staheli Index (ICC, 0.74–0.99). Conclusions: Footprint measurements collected with various techniques demonstrate differences. Interchangeable use of exact values without adjustment is not advised. Intrarater reliability of a single method (ink mat) was found to be high. (J Am Podiatr Med Assoc 102(2): 130–138, 2012)

Contact force ratio: A new parameter to assess foot arch function

Static footprint parameters have been used to quantify arch height with conflicting results. This could be caused by the inherent inaccuracy and variations of the methodology used. Since the foot is a dynamic structure that undergoes changes during a step, it is more desirable to capture and analyse the dynamic footprint at an instant during the gait cycle that can most closely reflect the weight-bearing foot function. Forty (40) volunteer subjects were recruited for the reliability test of a new parameter, the Contact Force Ratio (CFR), derived from dynamic footprint. This is a measure of midfoot loading during gait. The mid-gait dynamic footprints were collected using a pressure sensing mat. Results of ICC tests showed that the CFR had good intratester (0.918) and intertester (0.909) reliability. The validity of the method was examined by correlating the parameter to the functional change in arch height, i.e. the Navicular Drop between the non-weight-bearing and weight-bearing conditions.