HUBUNGAN KADAR FERRITIN DAN ASUPAN PROTEIN PADA IBU HAMIL TRIMESTER II-III DI KABUPATEN BOLAANG MONGONDOW UTARA

Ferritin is a kind of protein that is important in iron metabolism. In normal condition, ferritin saves iron that can be used again as a required. In iron overload, iron body store is greatly increased and there is much ferritin in the system, such as the liver and spleen. This study aimed to determine the relationship of ferritin and protein intake among pregnant women in North Bolaang Mongondow in 2015. This was an analytical study with a cross sectional design. The population was all pregnant women in North Bolaang Mongondow. There were 72 people as samples obtained with purposive sampling method. Low ferritin levels were found in 26 respondents (36.1%) while normal ferritin levels were found in 46 respondents (63.9%). There were 18 respodents (44.4%) with enough protein intake. Of the 18 respondents, there were 2 respodents (11.1%) with low ferritin levels and 16 respondents (88.9%) with normal ferritin levels. The chi-square test with a confidence level 95% showed that there was a significant correlation (P = 0,019) between the level of ferritin and protein intake among pregnant women. Conclusion: There was a significant correlation between the level of ferritin and protein intake in pregnant women II-III trimesters in North Bolaang Mongondow.Keywords:ferritin, protein intake, pregnant women.Abstrak: Feritin merupakan protein yang penting dalam metabolisme besi. Pada kondisi normal, ferritin menyimpan besi yang dapat diambil kembali untuk digunakan sebagai kebutuhan. Pada keadaan kelebihan besi, simpanan besi tubuh sangat meningkat dan jauh lebih banyak ferritin yang terdapat di jaringan, misalnya hati dan limpa.penelitian ini bertujuan untuk mengetahui kadar ferritin dan asupan protein rendah pada ibu hamil di Kabupaten Bolaang Mongondow Utara Tahun 2015. Protein merupakan zat pembangun jaringan, membentuk struktur tubuh, pertumbuhan, transportasi oksigen, dan membentuk sistem kekebalan tubuh. Jenis penelitian ini survei analitik dengan rancangan potong lintang. Populasi ialah seluruh ibu hamil di Kabupaten Bolaang Mongondow Utara. Terdapat 72 sampel yag diperoleh secara purposive sampling. Hasil kadar ferritin kurang sebanyak 26 responden (36,1%) sedangkan yang normal sebanyak 46 responden (63,9%). Terdapat 18 respoden (44,4%) dengan asupan protein cukup. Dari ke 18 responden tersebut, 2 respoden (11,1%) dengan kadar feritin kurang dan 16 responden (88,9%) dengan kadar feritin normal. Hasil uji Chi Square pada tingkat kepercayaan 95% menunjukkan terdapat hubungan antara kadar feritin dan asupan protein pada ibu hamil Di Kabupaten Bolaang Mongondow Utara (P = 0,019). Simpulan: Terdapat hubungan bermakna antara kadar ferritin dan asupan protein pada ibu hamil Trismester II-III di Kabupaten Bolaang Mongondow Utara.Kata kunci: ferritin, protein intake, ibu hamil

Effect of iron deficiency onTrichuris suisandAscaris suuminfections in pigs

The objective of this experiment was to detect a possible interaction between iron deficiency and intestinal nematode infections. We report on a 2×2 study where thirty-one 10-week-old pigs fed a low or a normal iron diet were infected with bothTrichuris suis(4500 eggs) andAscaris suum(1200 eggs). No significant difference was detected between diet groups with respect to parasitological parameters forA. suumor the total number of adultT. suisrecovered at necropsy 10 weeks p.i. However, in the low iron groupT. suiswere located more proximally and the worms were increased in length. A higher proportion of pigs with initial faecal egg excretion at 6 weeks p.i. was observed in the low iron group, indicating a shortened pre-patency period. Worm fecundity and total faecal egg excretion were also highest in the low iron group. A significant correlation was found between female worm length and fecundity. The peripheral eosinophil counts were diminished in the low iron host groups. The infected low iron group experienced more severe pathophysiological changes in terms of hypoalbuminaemia and decreases in erythrocyte volumes. A significant inverse correlation existed between iron content in the bone-marrow and liver (body) store. In conclusion, iron deficiency increased the severity ofT. suisinfection in pigs.

CHEMICAL FINDINGS IN THE BLOOD OF THE DOG AFTER TEMPORARY OBSTRUCTION OF THE PYLORUS

The toxemia characteristic of upper gastrointestinal tract obstruction may be produced by temporary obstruction of the pylorus. This procedure affords an opportunity for studying the toxemia in the absence of mechanical factors, operative risk, and infection. Animals which spontaneously recover from the toxemia may show a return of the blood chloride to normal when only distilled water is given. In such instances there must be a redistribution of the body store of chlorides. The administration of sodium chloride by mouth to animals which show a toxemia without evidence of spontaneous recovery causes a rapid return of the blood to normal. There is a marked diuresis with high nitrogen excretion during the toxemia. This is evidently due to the increased protein destruction. The return of the blood chlorides to normal causes a cessation of the increased protein destruction.