Titan Nickelide in the Treatment of Dystrophic Bone Cysts in Children

The aim of the study was to assess the efficiency of surgical treatment of patients with dystrophic bone cysts by the method of cyst cavity filling with fine-grain porous titanium nickelide. Methods. The research involved patients with dystrophic bone cysts. 30 patients had an operation of a single-stage opening of the cyst cavity and grafting the residual bone cavity with fine-grain titanium nickelide. Results. The applied treatment method was proven to be effective in the immediate postoperative and long-term periods.Conclusion. Clinical practice demonstrates that the method of dystrophic bone cyst treatment by opening of the cyst cavity with the following grafting with the granules of titanium nickelide gives more positive outcomes compared to the traditional method. This technology allows to reduce the number of post-operational complications and negative outcomes in the long-term perspective.

Plastics of sequestral cavities with fine grained titanium nickelide for chronic osteomyelitis

The goal of research. To assess the efficiency of surgical treatment of patients with chronic osteomyelitis by the use of grafting post - osteomyelitis cavity with fine-grain porous titanium nickelide. Methods. The research covered patients with chronic osteomyelitis, 60 patients were made an original operation of single stage sequestrectomy and grafting the residual bone cavity with fine-grain titanium nickelide. Results. There was demonstrated clinico-roentgenologic efficiency of this treatment method in early rehabilitation period and in further monitoring.Conclusions. Clinical practice confirms that the use of the treatment method of chronic osteomyelitis by sequestrectomy with the following grafting with the granules of titanium nickelide gives more positive results than the traditional method. It is less traumatic, simpler in realization. The use of this technology allows to reduce the number of post-operational complications and negative results in distant periods.

The use of fine - grained nickelide titanium, in the experiment, for the pathology of the musculoskeletal system.

The aim is to study and compare the processes of regeneration of bone tissue in animals while grafting titanium nickelide granules in bone cavities and free plastics in experiment. Methods. Two methods of bone grafting were experimentally reproduced to assess the speed of regeneration of bone tissue of dogs’. The first is traditional method with bone crumbs, and the second one of filling the bone cavity with fine-grain titanium nickelide. The last-named has been developed lately. In the first group consisting of 25 dogs, granules of porous titanium nickelide were placed in the formed cavity of shin bone epiphysis. In the second (control) group (consisting of 10 dogs), bone crumbs were introduced into the cavity of the shin bone. Results. The experiment showed that fine-grain titanium nickelide use for grafting bone cavity in comparison with bone crumbs demonstrated the formation of bone organo-typical regenerate 3 months faster. Conclusions. Fine-grain titanium nickelide is a promising material and can be used in the pathology of the skeleton.

Crystallization Features of Porous TiNi Made by SHS

The surface layers and fracture surfaces of porous titanium nickelide obtained by self-propagating high temperature synthesis (SHS) in a flow reactor in an argon atmosphere are studied by SEM and energy dispersive analysis. It is alleged that primary pores 5–15 µ in size and the related granular layer are formed due to segregation and capillary force effect during peritectic crystallization of some porous alloy areas. Coarsening and deformation of pores, as well as migration and growth of granular layers, is caused by reaction gases. Carbon and oxygen impurities present in the reaction gases and the protective atmosphere penetrate into the melt film on the pore surface to form strong and corrosion-resistant nanostructured layers of intermetallic carbides, nitrides and oxides.

Segregation in Porous NiTi Made by SHS in Flow Reactor

The research considers the contribution of gases to the surface formation during self-propagating high-temperature synthesis (SHS) of porous titanium nickelide based alloys. The structure of the obtained porous alloys was analyzed using the methods of secondary ion mass spectrometry (SIMS), optical microscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Nanocrystalline intermetallic oxycarbonitrides of a complicated structure were found on the porous titanium nickelide surface. A dense double gradient layer was found under the outer loose deposits. It is concluded that the dense gradient layer of intermetallic oxycarbonitride provides chemical passivity of the investigated porous alloys. Loose surface deposits of intermetallic oxycarbonitrides ensure successful integration of the alloy into the biological tissue in case of implantation.

Method for Glenoid Bone Defect Plasty in Recurrent Shoulder Instability

Technique for glenoid bone defect plasty in posttraumatic shoulder instability using the porous titanium nickelide (Ti-Ni) graft is presented. This method is an alternative to Latarjet operation and autoplasty with the graft from the iliac crest. The shape and size of the graft was determined by MSCT data and the graft was sawed out from cylindrical billets with diameter of about 2.5 cm and wall thickness - 1 cm. Two screw holes were drilled and the graft was placed into the defect. That technique was applied in 6 patients with long lasting history of recurrent anterior instability and instability relapses after shoulder stabilization using other surgical techniques. Preoperative shoulder functional state by Rowe scale averaged 35.0 points versus 93.3 points after operation. One year follow up showed no cases of instability relapse. The advantages of this technique are the possibility of accurate glenoid anatomic shape reconstruction, absence of graft resorption and reduction of intervention duration.

Method for Glenoid Bone Defect Plasty in Recurrent Shoulder Instability

Technique for glenoid bone defect plasty in posttraumatic shoulder instability using the porous titanium nickelide (Ti-Ni) graft is presented. This method is an alternative to Latarjet operation and autoplasty with the graft from the iliac crest. The shape and size of the graft was determined by MSCT data and the graft was sawed out from cylindrical billets with diameter of about 2.5 cm and wall thickness - 1 cm. Two screw holes were drilled and the graft was placed into the defect. That technique was applied in 6 patients with long lasting history of recurrent anterior instability and instability relapses after shoulder stabilization using other surgical techniques. Preoperative shoulder functional state by Rowe scale averaged 35.0 points versus 93.3 points after operation. One year follow up showed no cases of instability relapse. The advantages of this technique are the possibility of accurate glenoid anatomic shape reconstruction, absence of graft resorption and reduction of intervention duration.

Local cytokine status of experimental animalsat experimental intraocular implantationof titanium nickelide

An assessment of the level of pro- (IL1β, FNOα, IL2) and anti-inflammatory (IL10) cytokines in the intraocular fluid of experimental animals at 3, 7 and 30 days after experimental intraocular implantation of porous titanium nickelide TN-10 was carried out. It was found that the implantation of porous titanium nickelide as drainage material does not impact the pro-inflammatory and anti-inflammatory cytokines’ local balance. It does cause an increase of IL1β, IL2 and IL10 production to the end of the first week of monitoring as well as a substantial limitation of anti-inflammatory FNOα synthesis. However at the end of the 30 day monitoring period, local IL1β and IL10 concentrations corresponded to those of control animals. At the same time, of some significance are obtained data upon a modulation of a caused by the surgical procedure disbalance in the system of local pro- and anti-inflammatory cytokines which is observed at the titanium nickelide TN-10 intraocular implantation.