Comparative Vascular Anatomy of the Knee Joint Between the Human Being and Cynomolgous Monkey

Vascular anatomy of the knee joint in the cynomolgous monkey and human being was compared to determine if the nonhuman primate was an acceptable model for preserving the vascularity of certain tissues during human orthopaedic surgical procedures. Specimens, consisting of osseous tissue and replicas of existing arteries and arterioles, were created using the methyl methacrylate perfusion — soft tissue corrosion technique. Arterial supply to various structures of the knee joint in both species essentially arose from the same sources.

Rupture of an Experimentally Induced Aneurysm in a Primate

SUMMARYCerebral aneurysms are extremely rare in all animals except man. We report the occurrence of a carotid-ophthalmic aneurysm in a cynomolgous monkey two months following accidental occlusion of the ipsilateral cervical internal carotid artery. This was documented angiographically. The aneurysm was deliberately ruptured by the insertion and withdrawal of fine needles. This produced a large subarachnoid hemorrhage visualized on CT scan. There was a progressive severe fall in cerebral blood flow and moderate vasospasm. The neurological status deteriorated on the tenth day and the animal was sacrificed on day 13. On electron microscopy, the aneurysm showed a fibrous wall, and the endothelium showed balloon-like endothelial cells with gaps. Corrugations occurred in the inner aspect of the anterior circulation arteries.