Polycentric binding in complexes of trimethylamine-N-oxide with dihalogens

Dihalogens readily interact with trimethylamine-N-oxide under ambient conditions. Stable 1 : 1 adducts were obtained in a case of iodine chloride and iodine bromide. Formally monodentate ligands are bound in a polycentric manner.

Electrophilic ipso-Halocyclization of N-Phenyl-N-triflylpropiolamides Leading to 8-Halo-1-azaspiro[4.5]deca-3,6,9-trien-2-ones

N-Phenyl-N-triflylpropiolamides react with iodine chloride or iodine bromide by an intramolecular electrophilic ipso-halocyclization/nucleophilic halide addition sequence to furnish cyclohexadiene-spiro-γ-lactams. These products can undergo cleavage of the amide bond with primary amines and of the N–Cspiro bond with secondary amines, leading to N-alkyl-2-iodo-3-phenylacrylamides and N-(4-halophenyl)-2-iodo-3-(2-triflylamino)phenylacrylamides, respectively.

EVALUATION OF THE EFFECTIVENESS OF DISINFECTING ACTION OF MONOCHLORIDE (IODINE CHLORIDE) 2% IN PRODUCTION CONDITIONS

The results of production tests of the effectiveness of the disinfectant Monochloride (Iodine chloride) 2% for disinfection of objects of veterinary supervision are presented. Test results show that Monochloride (Iodine Chloride) 2% is effective disinfectant and can be recommended for preventive and forced disinfection at the objects of veterinary surveillance while monitoring its quality for the isolation of bacteria of the Escherichia coli group and staphylococci, as well as forced disinfection in infectious bacterial diseases (including tuberculosis) and viral etiology, especially dangerous infections (Siberian ulcer and other spore infections).

LABORATORY TESTS OF DISINFECTANT «MONOCHLORIDE (IODINE CHLORIDE) 2%»

The article describes the results of laboratory tests of the effectiveness of the disinfectant Monochloride (Iodine chloride) 2%. Laboratory studies were carried out on test objects and test surfaces contaminated with test cultures of microorganisms, which included museum cultures of E. coli (E. coli 1257), S. aureus 209-P, mycobacteria (pcs. B5), and spores (B. cereus pieces. 96). Disinfection of test objects was carried out by the method of irrigation at a consumption rate of 0,25...0,3 l/ m2 with disinfection of smooth surfaces and 0,5 l/m2, with disinfection of rough surfaces. The treatment was performed twice with an interval of 60 minutes. Our work established that the Monochloride (Iodine chloride) 2% has a high disinfectant activity against Escherichia coli, Staphylococcus aureus, mycobacteria and spores. On the basis of the laboratory work, this tool can be recommended for production tests at veterinary surveillance facilities.

The peculiarity of intercalation of carbon nanomaterials containing nanotubes

The possibility of intercalation of carbon nanomaterials containing carbon nanotubes is considered. Carbon nanomaterials containing multiwall carbon nanotubes of different structure and size were intercalated by iodine chloride with use standard one-temperature method. As it is shown by electron microscopic studies, after intercalation the size and morphology of carbon nanotubes are essentially changed. The diameter of carbon nanotubes increases two times more. This increase in diameter is due to the penetration of iodine chloride molecules between layers of a multiwall carbon nanotubes or into the inner cavity of nanotubes. According to X-ray diffraction, the position of the most intense band in the 00ldiffractogram of carbon nanomaterial moves to the region of smaller angles after intercalation. The exact angular position of the 00l-band corresponds to reflection from the intercalate layers for the third stage compound. The hysteresis in the temperature dependence of resistivity for compacted intercalated carbon nanomaterial is observed. This hysteresis is explained by the change of the charge carriers effective relaxation time at the scattering on the phonons of the graphite layer and the intercalate layer. Such change occurs at the phase transitions in the intercalate layers from an ordered "quasicrystalline state" to an unordered "quasiliquid" state.

Stereocontrolled synthesis of rosuvastatin calcium via iodine chloride-induced intramolecular cyclization

A novel, stereoselective approach towards rosuvastatin calcium from the known (S)-homoallylic alcohol has been developed.