Village Government Efforts in Realizing the Highest National Building Village Index (IDM) in Ngroto Village

Every government program certainly has the support of the local government to the bottom, such as the village government. Likewise, with the Village Building Index (IDM) program, of course, every local government is racing to succeed even, by all means, will try to get achievements from the program. But in the Ngroto Village Government, by carrying out village government functions as usual, by existing rules get achievements as a village with the highest IDM score at the National level in 2018. This research uses qualitative methods with the approach of intrinsic case study Robert K. Yin. Indeed, this approach received a lot of criticism since its emergence because it was considered weak analysis, not objective, and full of bias, but in research not only “why,” but also “how” Ngroto Village Government with its habit got maximum results. With this approach, researchers can explore and elaborate in-depth and comprehensively. The case study wants to know more deeply when the village government is not oriented towards achievement or achievement can become the village government with the highest national score. The village government applies legal regulations such as the implementation of musdes and musdus to filter aspirations and involve the community in planning development programs (participatory). Such efforts continue to be carried out by the village government to achieve achievements and are now a pilot center for other village governments.

Financial Burden of Stroke Reflected in a Pilot Center for the Implementation of Thrombolysis

Stroke represents a serious illness and is extremely relevant from the public health point of view, implying important social and economic burdens. Introducing new procedures or therapies that reduce the costs both in the acute phase of the disease and in the long term becomes a priority for health systems worldwide. The present study quantifies and compares the direct costs for ischemic stroke in patients with thrombolysis treatment versus conservative treatment over a 24-month period from the initial diagnosis, in one of the 7 national pilot centres for the implementation of thrombolytic treatment. The significant reduction (p < 0.001) of the hospitalization period, especially of the days in the intensive care unit (ICU) for stroke, resulted in a significant reduction (p < 0.001) of the total average costs in the patients with thrombolysis, both at the first hospitalization and for the subsequent hospitalizations, during the period followed in the study. It was also found that the percentage of patients who were re-hospitalized within the first 24-months after stroke was significantly lower (p < 0.001) among thrombolyzed patients. The present study demonstrates that the quick intervention in cases of stroke is an efficient policy regarding costs, of Romanian Public Health System, Romania being the country with the highest rates of new strokes and deaths due to stroke in Europe.

Data-work for personalized care: Examining nurses’ practices in remote monitoring of chronic patients

Healthcare professionals are increasingly working with data in their care delivery practices. However, there is limited understanding of how data work is enabling novel practices. This study focuses on novel nursing practices emerging in the context of remote monitoring of chronic patients. Specifically, we analyze how personalization of care is achieved in practice through data work. The study is based on a case of a pilot center in Norway where nurses provide remote care to patients by using a specialized system. We examine the practices of the nurses and how data in the form of graphs, alerts, questionnaires and messages are used to personalize care. We identify three main practices of data work for personalization: preparatory work, continuous adjustment and question fine-tuning. Finally, we discuss the pivotal role of nurses’ data work for personalized care in remote care.

Variabilidad genética y detección de error en filiación utilizando microsatélites en dos rebaños de alpacas Huacaya (Vicugna pacos)

Objetivo: Determinar la variabilidad genética y evaluar la utilidad de microsatélites (STR) en la determinación de paternidad en alpacas blancas huacaya, pertenecientes al Centro Piloto de Mejoramiento Genético Munay Paqocha y el Fundo Itita, de la Sociedad Peruana de Criadores de Alpacas y Llamas (SPAR) Puno. Realizar la genotipificación y selección de marcadores STR útiles para la asignación de paternidad y parentesco. Metodología: Se evaluaron 10 marcadores STR a partir de ADN aislado de sangre y de folículos pilosos de 183 individuos colectados al azar procedentes de dos rebaños. Resultados y Conclusiones: Se observó un alto nivel de variabilidad alélica en el total de individuos analizados, y la presencia de alelos exclusivos entre poblaciones, con frecuencias menores al 1,5% en los loci LCA37, LCA90, LCA5, VOLP92, YWLL36, YWLL44 y YWLL08. Se propone la incorporación de tres marcadores adicionales, VOLP92, LCA94 y LCA90 para los análisis de variabilidad genética en alpacas. Los valores de FIS (0,016), y FST (0,003) reflejaron bajo niveles de endogamia. El rebaño del Fundo Itita presentó una mayor Ho (0,858) respecto a la He (0,848), mientras que por el contrario el rebaño del Centro Munay Paqocha presentó un menor valor de la Ho (0,815) respecto a la He (0,848), con una tendencia al déficit de heterocigotos. Los 10 marcadores presentaron una probabilidad de exclusión de parentesco adecuada, con un valor superior al 99,9%, cuando se conoce el genotipo de ambos padres, y un poder de discriminación mayor a 0,90. Además, se alcanzó un valor PEC de 0,999 considerando solo los marcadores YWLL08, YWLL44, LCA37, YWLL36, LCA8; siendo YWLL08 el de mayor valor (0,885). La prueba de filiación permitió detectar mayores errores de asignación de maternidad (13,04%) y paternidad (30,4%) en el rebaño del Fundo Itita, en comparación a Munay Paqocha con errores de designación de maternidad de 7,69% y de paternidad de 17,95%, concluyendo que este centro posee un mejor registro de empadres. ABSTRACT:Aim: To determine the genetic variability and the selection of STR markers useful for the evaluation of inbreeding, assignment of paternity and kinship, and the genotyping of two breeding herds of white huacayas alpacas Vicugna pacos, from the Pilot Center for Genetic Improvement Munay Paqocha and Fundo Itita, in Puno Perú. Methodology: 10 STR markers were assessed in 183 individuals, randomly selected. Results and Conclusions: We observed a high level of allelic variability in the total individuals, and unique alleles among populations with frequencies lower than 1.5% in loci LCA37, LCA90, LCA5, VOLP92, YWLL36, YWLL44 and YWLL08. We propose the addition of three markers, VOLP92, LCA94 and LCA90 for the genetic variability analysis in alpacas. FIS (0.016) and FST (0.003) values reflected low levels of inbreeding. Fundo Itita herd showed higher Ho (0.858) than He (0.848), while the herd of Munay Paqocha showed lower Ho (0.815) respect to He (0.848), with trending heterozygote deficit. The 10 markers showed an appropriate exclusion relationship probability, with a value greater than 99.9% when the genotype of both parents was known, and a power of discrimination greater than 0.9. In addition, a PEC value of 0.999 was reached considering only markers YWLL08, YWLL44, LCA37, YWLL36, LCA8; YWLL08 being the highest value (0.885). Filiation test detected major errors of maternity (13.04%) and paternity (30.4%) in the herd Fundo Itita. In Munay Paqocha with respect to errors designation maternity 7.69% and paternity of 17.95%, concluding that Munay Paqocha had a better record of matings.