The ELIXIR channel in F1000Research

ELIXIR, the European life science infrastructure for biological information, is a unique initiative to consolidate Europe’s national centres, services, and core bioinformatics resources into a single, coordinated infrastructure. ELIXIR brings together Europe’s major life-science data archives and connects these with national bioinformatics infrastructures - the ELIXIR Nodes. This editorial introduces the ELIXIR channel in F1000Research; the aim of the channel is to collect and present ELIXIR’s scientific and operational output, engage with the broad life science community and encourage discussion on proposed infrastructure solutions. Submissions will be assessed by the ELIXIR channel Advisory Board to ensure they are relevant to ELIXIR community, and subjected to F1000Research open peer review process.

The ELIXIR channel in F1000Research

ELIXIR, the European life science infrastructure for biological information, is a unique initiative to consolidate Europe’s national centres, services, and core bioinformatics resources into a single, coordinated infrastructure. ELIXIR brings together Europe’s major life-science data archives and connects these with national bioinformatics infrastructures - the ELIXIR Nodes. This editorial introduces the ELIXIR channel in F1000Research; the aim of the channel is to collect and present ELIXIR’s scientific and operational output, engage with the broad life science community and encourage discussion on proposed infrastructure solutions. Submissions will be assessed by the ELIXIR channel Editorial Board to ensure they are relevant to ELIXIR community, and subjected to F1000Research open peer review process.

Experimental Investigation of Inertial Mixing in Droplets

Achieving the fast mixing requirements posed by the chemical, biological, and life science community for confined microchannel flows remains an engineering challenge. The viscous and surface tension forces that dominate conventional micro-flows undermine fast, efficient mixing. By increasing the collisional velocity of reagent droplets, inertia can be exploited to increase mixing rates. This paper experimentally investigates inertial droplet mixing in micro flows. A high speed, gaseous flow is used to detach, transport, and collide droplets of nanoliter-size volumes in standard T and Y-junction microchannel geometries. Mixing rates are quantified using differential fluorescent optical diagnostics. Measured droplet mixing times are compared to the characteristic time scales for mass and viscous diffusion and bulk convection. Results show that mixing times are decreased as the droplet inertia is increased, indicating the potential benefit of inertia-driven mixing.