Strengthening the Research Base That Informs STEM Instructional Improvement Efforts: A Meta-Analysis

We present results from a meta-analysis of 95 experimental and quasi-experimental pre-K–12 science, technology, engineering, and mathematics (STEM) professional development and curriculum programs, seeking to understand what content, activities, and formats relate to stronger student outcomes. Across rigorously conducted studies, we found an average weighted impact estimate of +0.21 standard deviations. Programs saw stronger outcomes when they helped teachers learn to use curriculum materials; focused on improving teachers’ content knowledge, pedagogical content knowledge, and/or understanding of how students learn; incorporated summer workshops; and included teacher meetings to troubleshoot and discuss classroom implementation. We discuss implications for policy and practice.

Decreased quality of life and treatment satisfaction in patients with latent autoimmune diabetes of the adult

Objectives Our main aim was to assess the quality of life (QoL) and treatment satisfaction (TS) of subjects with LADA (latent autoimmune diabetes of the adult) and compare these measures with those of patients with other diabetes types, i.e., type 1 (T1DM) and type 2 diabetes mellitus (T2DM). Methods This was a cross-sectional study with a total of 48 patients with LADA, 297 patients with T2DM and 124 with T1DM. The Audit of Diabetes-Dependent Quality of Life (ADDQoL-19) questionnaire and the Diabetes Treatment Satisfaction Questionnaire (DTSQ) were administered. Relevant clinical variables were also assessed. The data analysis included comparisons between groups and multivariate linear models. Results The LADA patients presented lower diabetes-specific QoL (p = 0.045) and average weighted impact scores (p = 0.007) than the T2DM patients. The subgroup of LADA patients with diabetic retinopathy (DR) who were treated with insulin had a lower ADDQoL average weighted impact score than the other diabetic groups. Although the overall measure of TS was not different between the LADA and T2DM (p = 0.389) and T1DM (p = 0.091) groups, the patients with LADA showed a poorer hyperglycemic frequency perception than the T2DM patients (p < 0.001) and an improved frequency of hypoglycemic perception compared with the T1DM patients (p = 0.021). Conclusions The current findings suggest a poorer quality of life, especially in terms of DR and insulin treatment, among patients with LADA compared with those with T1DM and T2DM. Hyperglycemia frequency perception was also poorer in the LADA patients than in the T1DM and T2DM patients. Further research with prospective studies and a large number of patients is necessary.

Porosity in Spray-Formed Materials

Porosity in spray-formed materials is an important issue, but the formation of porosity is not completely understood. Many experimental results and some theoretical models have been presented in the past. Nevertheless, the prediction of porosity in a deposit is still not possible today. The paper will give some examples picked from literature, which show some general correlations between process parameters and porosity. These correlations can be helpful to form a basic understanding of the process. Finally it is necessary to know more about the conditions of the droplets and the deposit at the point of impingement. These impacting conditions have to be correlated to the porosity to improve the understanding of the process and to make a prediction possible. Determining the impact conditions is a challenge because usually they are not constant with time and some values are difficult to measure. Our experiments show a strong correlation between the surface temperature of the deposit and the porosity. For IN718 and U720 as-sprayed porosities below 1 vol.% were achieved if the deposit surface temperature is app. 1250 °C. The average impact angle weighted by the local particle mass flux is also an important parameter. The probability of low as-sprayed porosity is high if the average weighted impact angle is below 25° but decreases dramatically for higher impact angles.