Laparoscopic adrenalectomy for suspected adrenal mass in lung cancer: ganglioneuroma

Background: Adrenalectomy is the gold standard for the treatment of primary adrenal ganglioneuroma. Preoperative differential diagnosis of ganglioneuroma is difficult and histopathologic examination is required to confirm the diagnosis. Patient: A 61-year-old woman, who was followed and treated by the medical oncology department because of lung carcinoma pathology squamous cell T4N0Mx, presented to our clinic due to a 15×8-mm nodule with a calculated relative wash-out rate of 40% in the right adrenal gland lateral edge, which was observed on computed tomography examination. Conclusion: Adrenal ganglioneuroma is a rarely seen, hormonally inactive, benign tumor. Final diagnosis can be made with histopathologic examination. Adrenalectomy is the standard treatment preferred for ganglioneuroma. Knowing the clinical appearance and good pathologic specialization are important adjunct matters in diagnosis. Laparoscopic adrenalectomy has become the gold standard in most patients with adrenal tumors.

INCIDENTAL PRESENTATION OF ADRENAL GANGLIONEUROMA: CASE SERIES AND REVIEW OF LITERATURE

Adrenal Ganglioneuromas are uncommon tumours arising from neural crest cells in posterior mediastinum and retroperitoneum. Rarely do they arise from adrenal gland and most of them are incidentally detected and hormonally inactive. Radiologically, they appear as any other adrenal mass, hence histopathological examination and immunohistochemistry plays a major role. With the advent of laparoscopy and robot, outcome of surgical treatment has improved a lot.