Cholecystectomy for Resistant Metastatic Malignant Melanoma of the Gallbladder: A Case Report

Malignant melanoma is an unpredictable disease, known to metastasize early even in thin melanomas. Historically the presence of intraabdominal metastasis meant poor prognosis with a 5-year survival of less than 20%. That has significantly changed with effective systemic therapy (EST), with most recent studies reporting 5-year survival of up to 50%. Metastasecectomy for resistant disease has been considered in Stage IV disease, however there is very little literature on the combination of EST and metastasectomy. This report describes a case of Stage IV malignant melanoma patient who developed resistant disease within her gallbladder fundic wall. She underwent open cholecystectomy, with complete metabolic response at 1-year follow up PET.

Primary Melanoma of Testis- A Case Report

Primary melanoma of the testis is very rare. Melanoma of testis usually occurs as metastatic tumor. Here we present a case of 54 year old man with right testicular swelling proven to be primary malignant melanoma. Patient had right scrotal swelling of six months duration. With raised LDH and unremarkable Serum β-HCG and Alpha Feto Protein level and with a suscipicion of primary testicular tumor on MRI, right inguinal orchidectomy was done. Its clinical presentation and histopathological examination is discussed here.