More often than not, we’re in sync: patient and caregiver well-being over time in stem cell transplantation

Background Hematopoietic stem cell transplantation (HSCT) is an aggressive medical procedure which significantly impacts the shared emotional well-being of patients and family caregivers (FC). Prior work has highlighted the significant overlap in well-being among patients and FCs; however, how this interdependence may change over the course of HSCT has received less attention. Methods We conducted secondary analyses of a supportive intervention delivered to 154 FCs of HSCT patients and examined relationships at baseline, 6 weeks, 3 and 6 months post-HSCT. Actor Partner Interdependence Modeling examined patient quality of life (QOL) and FC anxiety/depression. Results The data did not fit a multigroup approach limiting our ability to test intervention effects; however, bivariate analyses indicated FC depression significantly correlated to patient QOL at baseline (r = − .32), 6 weeks (r = − .22) and 6 months post-HSCT (r = − .34; p’s < .05); whereas FC anxiety was only correlated with patient QOL at the first two timepoints (p’s < .05). There was an unexpected, partner effect such that worse patient QOL at 6-weeks significantly related to lower FC depression at 3-months (B = .193; p = .026) and changed direction with patient QOL at 3-months being related to more FC depression at 6-months (B = − .187; p = .001). Conclusions These findings highlight the significant, yet nuanced, interdependence of patient QOL and FC well-being during HSCT. Specifically, greater interdependence was observed between patient QOL and FC depression compared to FC anxiety, suggesting potential treatment targets for patients and their families. Trial was registered at ClinicalTrials.gov Identifier: NCT02037568; first registered: January 16, 2014; https://clinicaltrials.gov/ct2/show/NCT02037568

Mediating effect of Maternal and Paternal Family Relationship between Neuroticism and Postpartum Depression: The Actor-Partner Interdependence Mediation Model

Purpose: The purpose of this study is to analyze the mediating effect of family relationship between personality traits and postpartum depression by using the Actor-Partner Interdependence Mediation Model (APIMeM).Methods: Participants were 197 married couples within one year of childbirth. The APIMeM using path analysis was used to determine direct and indirect effects of personality and family relationships on postpartum depression between wives and husbands in AMOS 22.0.Results: Data showed an actor effect suggesting that the higher the neuroticism level in wives, the higher the postpartum depression level. In husbands, data indicated an actor effect suggesting that the higher the neuroticism level in husbands, the higher the postpartum depression level; however, neither wives nor husbands showed a partner effect. Data showed an actor effect suggesting that the higher the family relationship level for both wives and husbands, the lower the postpartum depression level; however, neither wives nor husbands showed a partner effect. Data showed a mediating effect of neuroticism in wives on postpartum depression through the family relationship.Conclusion: The study results indicate that, to prevent postpartum depression, it is necessary to develop a nursing intervention program for couples that can improve the personalities and family relationship of couples.

“Don’t be so Harsh”: Influence Tactics, Support Transactions, and Relationship Satisfaction

The current study examined the association between both partners’ perceptions of the other partner's use of influence tactics during conflicts (harsh vs. soft) and both partners’ relationship satisfaction. Using a dyadic approach, the mediating role of support transactions (i.e., given and received support) was also examined. One-hundred and thirteen couples filled out questionnaires regarding partners’ use of influence tactics, received and given support, and relationship satisfaction. Results indicated one partner effect; namely, women's received support was found to be a mediator between women's perception of their partners’ use of harsh tactics and both partners’ satisfaction. There was only one actor mediation effect of given support and that was observed among women alone; namely, given support mediated the association between harsh tactics and women's relationship satisfaction. Gender and support transaction may play an important role in explaining the link between harsh tactics and relationship satisfaction.

Adolescent sibling associations among alcohol, cannabis, and sexual risk behavior: A test of interdependence

Although siblings are conceptualized as a salient social influence during adolescence, few studies have examined how adolescent siblings influence each other’s substance use and risky sexual behavior. This study’s objective was to investigate the influence of alcohol use days, cannabis use days, and cannabis and alcohol co-use days on the sexual risk behavior of siblings while accounting for dyadic influence. At the baseline visit for a randomized controlled trial for adolescents referred due to parents’ concerns about their substance use (“referred adolescents”; n=99; Mage=15.95), we assessed alcohol and cannabis use days as well as sexual risk behavior of the referred adolescents and their sibling (Mage=15.03). We computed the number of days in the 30 days prior to the baseline that alcohol and cannabis use occurred on the same day. Using a cross-sectional actor partner interdependence model, we tested two models of how adolescents’ substance use is associated with their own (“actor effect”) and their siblings’ (“partner effect”) sexual risk behavior—one model for alcohol and cannabis use, and one model for co-use. Results indicated for referred adolescents and their siblings, within an individual, greater alcohol, cannabis, and co-use was significantly associated with sexual risk behavior (actor effects). Furthermore, more sibling co-use days were positively associated with referred adolescent sexual risk behavior (partner effect), representing interdependence. These findings confirm the influence siblings have on one another’s risky behavior in adolescence and have implications for prevention and intervention efforts for adolescent substance use.

Cationic yet Stronger Donor: A Surprising Partner Effect and the Partner Strategy in Accelerating a Pincer-Co Catalyzed Nitrile Hydroboration Reaction

A strategy to tune the catalytic behavior of a organometallic catalysts rather than ligand engineering is suggested in this work, by computationally studying the effect of (18-crown-6)K+, W(CO)3 and W(PMe3)3 on the reactivity of a Pincer-Co catalyzed nitrile hydroboration reaction through π-coordination to the ligand aromatic ring. These extra additives, as called by the partners, binds the central phenyl ring of the ligand by either dispersion or chemical bonding. The electron-richness of the cobalt center is tuned by the partner, and follows the order (18-crown-6)K+ > W(PMe3)3 > no partner > W(CO)3. While the influence of covalent W-containing partners parallels the electron-richness of W, the non-covalent partner, (18-crown-6)K+, surprisingly increases the donor ability of the Pincer ligand, through polarization effect. All the elementary steps involved in the nitrile hydroboration reaction are influenced by the partner, and the overall barrier is lowered by a surprisingly large extent of 4.9 kcal/mol in the presence of (18-crown-6)K+, suggesting a charming partner effect to be explored by experimentalists that the reactivity of a catalyst can be consecutively tuned without ligand modification.

Dyadic Cancer-Related Distress and The Role Of Mindfulness and Spiritual Well-Being in Couples with Cancer: An Actor-Partner Interdependence Model

The present study draws attention to the significance of considering mindfulness and spiritual well-being on cancer-related distress among couples with cancer during the pandemic. Dyadic data was analyzed among couples with cancer (80 couples; N=160) to examine the within-person (actor effects) and between-partner (partner effects) associations among links between mindfulness, spiritual well-being, and cancer-related distress through the use of the actor-partner interdependence model (APIM; Kashy &amp; Kenny, 2000). Significant actor and/or partner effects were found for mindfulness and spiritual well-being in couples with cancer, a factor that predicted cancer-related distress. Spirituality seemed to only play an important role in patients’ own cancer-related distress (actor effect), with patients’ higher levels of spiritual well-being predicting patients’ lower levels of distress. On the other hand, mindfulness was not only significantly related to the cancer patient and partner’s own distress (actor effect), partner’s mindfulness was also significantly associated with the patient’s distress (partner effect). The findings underscore the need to adopt a systemic perspective that accounts for multiple, simultaneous adaptive processes including mindfulness and spiritual well-being as influences on cancer-related distress in the time of COVID-19.

What Bots Can (and Can’t) Do? (Model of Protest and Counter-Protest Political Mobilization)

Despite the increasing interest among scholars in the effect of Internet bots, or automated social media accounts, on the processes of political communication and mobilization in the online sphere, the extent of bots’ effectiveness and the specific mechanisms of their use remain largely understudied. The deficit of the overarching conceptual understanding and concrete results is arguably due to researchers’ aspiration to solve a problem in the empirical way, without attempting to combine data analysis with mathematical and computational modeling. Having analyzed the existing models on the topic, the authors offer their own model that is based on the spiral-of-silence theory. The key features of the model that set it apart from the existing ones are the following: a) taking into account differences in the types of motivation and costs associated with expressing protest and loyalist sentiments; b) including “partner effect” into the spiral-ofsilence mechanism; c) employing a neurological decision-ma king scheme according to which the same stimulus can prompt action and be a deterrent. On the basis of a series of computational experiments with the model, the authors demonstrate that bots are more effective in mobilizing opposition members when an individual motivated for political participation refrains from it because his local social community does not share his views. In this case, the emergence of a like-minded partner bot can destroy the spiral of silence created by this community and encourage this individual to openly express his position. On the contrary, when mobilizing loyalists, bots are most effective in relation to poorly motivated individuals. The model elaborated by the authors not only allows us to evaluate bots’ effects in a new way, but it also sheds light on how people make decisions in the framework of political communication and mobilization in social networks.

Associations between self-efficacy, distress and anxiety in cancer patient-relative dyads visiting psychosocial cancer support services: Using actor-partner interdependence modelling

Background Patients with cancer and their relatives often suffer from psychosocial burdens following a cancer diagnosis. Psychosocial cancer support services offer support for cancer patients and their relatives. Only a few studies have focused on associations of psychological factors within patient-relative dyads. This study aims to assess associations between the patients’ or relatives’ self-efficacy and their levels of distress and anxiety who seek help together at psychosocial cancer support centres. Methods Participants were recruited at two psychosocial cancer support centres in a major city in Germany. Patients with cancer and their relatives seeking support together received the questionnaire before their first support session. Self-efficacy was assessed with the Pearlin sense of mastery scale, distress with the distress thermometer and anxiety with the General Anxiety Disorder questionnaire (GAD-7). For the analysis, the actor-partner interdependence model was applied. Results The data analysis was based on 41 patient-relative dyads (patients: 39% women, mean age 53.5; relatives: 66% women, mean age 52.16). A significant actor effect from self-efficacy to distress was found for patients (r = -0.47) but not for relatives (r = -0.15). Partner effects from self-efficacy to distress were not significant (r = -0.03, r = -0.001). The actor effect from self-efficacy to anxiety for patients (r = -0.61) as well as relatives was significant (r = -0.62), whereas the partner effect was significant for patients (r = 0.16) but not for relatives (r = -0.46). Conclusion The results suggest that patients’ and relatives’ self-efficacy is associated with their distress and anxiety. Partner effects were visible for patients’ self-efficacy and relatives’ anxiety. These findings suggest that self-efficacy is an important factor for the psychological well-being of patients and relatives and that it may additionally be associated with the partners’ well-being. Longitudinal research with larger samples is needed to support the findings.

Coparenting and Mental Health in Families with Jailed Parents

The number of families affected by parental incarceration in the United States has increased dramatically in the past three decades, with primarily negative implications for adult mental health and child and family well-being. Despite research documenting increased strain on coparenting relationships, less is known regarding the relation between adult mental health and coparenting quality. This study investigated coparenting in families with young children currently experiencing parental incarceration. In a diverse sample of 86 jailed parent–caregiver dyads (n = 172), this analysis of a short-term longitudinal study examined the links among jailed parents’ and children’s at-home caregivers’ externalizing mental health symptoms and perceived coparenting alliance quality using the Actor–Partner Interdependence Model. Analyses using structural equation modeling revealed a medium sized negative partner effect for externalizing behaviors on coparenting alliance for jailed parents, wherein caregivers increased externalizing symptoms related to jailed parents’ lower reported coparenting quality. Caregiver–partner effects and both actor effects resulted in small effects. These findings highlight the roles of mental health and coparenting relationship quality when a parent is incarcerated and contribute to the existing literature on incarcerated coparenting, with implications for theory and practice.

Couples undergoing Assisted Reproductive Techniques: An Actor-Partner Interdependence Model of dyadic adjustment, attachment, and body-image avoidance

The aim is to assess the commonalities and interdependence referred to body-image avoidance among 118 couples newly introduced to first-level assisted reproductive techniques. Results showed non-clinical functioning levels, and partners showed a correlated, yet low, dyadic adjustment. The couple-effect was modeled through an Actor Partner Interdependence Model. For both partners, dyadic adjustment’s actor-effect associates with body-image avoidance. Moreover, psychological symptoms’ actor-effect associate to body-image avoidance, resulting significantly more influential than the partner-effect. Only for males, alexithymia’s actor-effect was significant. To conclude, partners’ functioning is quite specular yet not interdependent, as they do not show a couple-as-a-unit modality of functioning. Clinical implications are discussed.