Histopathological Evaluation of Ficus Capensis Aqueous Extract on Liver, Kidney, Intestine and its Potentials in Treatment of Anaemia

Ficus capensi is a nature of Nigerian multi ethnic group and it is been identified and called differently dy ethnic groups for example, igbo call it akporo, hausa -uwaryara,etc. The aim of the this research titlled; Histopathologica evaluation of ficus capensis ethanol extract on liver, kidney, intestine and it potentials in the treatment of anaemia is to evaluate the effect of leaf and stem back extract of ficus capensis in the treatment potential of anaemia and it’s histopathological effect on liver, kidney, and large intestine of wister rat. The animals were grouped into 5(A, B, C, D & E) and anaemia induced with cirfuroxime in all the groups except group E which is the negative control whereas other groups were treated with vitamins and leaf & stem bark of Ficuscapensis ethanol extract; group C wasn’t treated and it’s regarded as positive control. The blood sample were collected suing cardiac puncture and liver,kidney and large intestine were all harvested following dissection upon 14 days treatment and experimental termination. All the samples collected were analysed using standard methods. There was significant difference in body weight, same was observed in multiple comparism test on packed cell volume and haemoglobin after treatment with Vitamins, leaf and stem bark of Ficus capensis ethanol extract. It was also observed that there was relative distortion of large intestinal lumen, kidney and hepatocytes. Ficusis capensis leaf and bark has shown antianaemic potentials, however; its toxic effect on the selected organs (liver, Kidney and large intestine) called for caution among users.

Facile and Rapid Isolation of Oxypeucedanin Hydrate and Byakangelicin from Angelica dahurica by Using [Bmim]Tf2N Ionic Liquid

Ionic liquids (ILs) have sparked much interest as alternative solvents for plant materials as they provide distinctive properties. Therefore, in this study, the capacity of ILs to extract oxypeucedanin hydrate and byakangelicin from the roots of Angelica dahurica (A. dahurica) was investigated. The back-extraction method was examined to recover target components from the IL solution as well. Herein, [Bmim]Tf2N demonstrated outstanding performance for extracting oxypeucedanin hydrate and byakangelicin. Moreover, factors including solvent/solid ratio, extraction temperature and time were investigated and optimized using a statistical approach. Under optimum extraction conditions (solvent/solid ratio 8:1, temperature 60 °C and time 180 min), the yields of oxypeucedanin hydrate and byakangelicin were 98.06% and 99.52%, respectively. In addition, 0.01 N HCl showed the most significant ability to back-extract target components from the [Bmim]Tf2N solution. The total content of both oxypeucedanin hydrate (36.99%) and byakangelicin (45.12%) in the final product exceeded 80%. Based on the data, the proposed approach demonstrated satisfactory extraction ability, recovery and enrichment of target compounds in record time. Therefore, the developed approach is assumed essential to considerably reduce drawbacks encountered during the separation of oxypeucedanin hydrate and byakangelicin from the roots of A. dahurica.

Partitioning of minor actinides from HLLW using the DIAMEX process.Part 1 - Demonstration of extraction performances and hydraulic behaviour of the solvent in a continuous process

The French DIAMEX process shows very promising capabilities in separating minor actinides from HLLW. A counter-current centrifugal extractor experiment has been conducted to investigate the capabilities and possibilities of the DIAMEX process (hydraulic and extraction behaviour), for the separation of lanthanides from a simulated High Level Liquid Waste (HLLW), corresponding in concentration to a raffinate from the PUREX process.A ´´hot´´ batch test, using genuine HLLW, and a continuous counter-current experiment have verified the excellent extraction and hydraulic behaviour, respectively.With only four extraction stages in the cold experiment, lanthanide decontamination factors were higher than 2000, except for europium. Co-extraction of molybdenum and zirconium was efficiently prevented using oxalic acid in the feed solution. The back-extraction was very efficient, yielding in 4 stages more than 99% recovery of lanthanides. Palladium and ruthenium were more difficult to back-extract and for these elements further investigations are needed.

Determination of 4-Hydroxy-3-Methoxymandelic Acid in Urine using HPLC with Electrochemical Detection

A method is described for the assay of 4-hydroxy-3-mcthoxymandelic acid (HMMA) in urine using IIPLC coupled with electrochemical detection. In this method acidified urine is extracted with ethyl acetate which is then washed with the chromatography solvent to back extract HMMA. The solvent is a pH 50 citrate buffer. At this pH, HMMA separates clearly from all other electroactive compounds present in urine.

Argon Plasma Emission Spectrometry of Uranium in Phosphatic Materials

A method is described for the determination of uranium by using a dc argon plasma emission spectrometer. Problems and interferences found in the method previously reported are overcome by using an improved sample pretreatment. A new synergistic system, 2% oxalic acid adjusted to pH 4.5 with triethanolamine, is used to quantitatively back-extract uranium from trioctylphosphine oxide in cyclohexane. This improved method yields excellent results for >1 ppm uranium in nitric and hydrochloric acid solutions of phosphate rocks, phosphoric acids, phosphate fertilizers, phosphogypsums, organic phosphates, and waste solutions. Recovery data are given for synthetic and certified standards.