lamellar material
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2019 ◽  
Vol 31 (3) ◽  
pp. 378-381 ◽  
Author(s):  
Dayna A. Goldsmith ◽  
Aslı Mete ◽  
Joseph B. Pesavento ◽  
John M. Adaska

Pulmonary alveolar proteinosis (PAP) is a disease of surfactant clearance in which functional abnormalities in alveolar macrophages lead to accumulation of surfactant within alveoli in mammals. Histologic examination of 6 avian autopsies, including 4 chickens, a turkey, and a cockatiel, revealed accumulation of hypereosinophilic densely arrayed lamellar material in the lungs that was magenta by periodic acid–Schiff stain and diastase resistant. Transmission electron microscopy of the proteinaceous material in 2 cases demonstrated alternating electron-dense and electron-lucent lamellae that formed whorls and had a regular periodicity of 6–14 nm, consistent with pulmonary surfactant. Given the anatomic differences between avian and mammalian lungs, we designated the presented condition “pulmonary proteinosis,” which can be observed as both an incidental finding or, when severe, may be a contributing factor to death through respiratory failure.


2018 ◽  
Vol 57 (12) ◽  
pp. 6778-6782 ◽  
Author(s):  
Jian Lin ◽  
Hongliang Bao ◽  
Meiying Qie ◽  
Mark A. Silver ◽  
Zenghui Yue ◽  
...  

Author(s):  
Lúcio Flávio Moreira Cavalcanti ◽  
Felisbela Maria Da Costa Oliveira ◽  
Evenildo Bezerra de Melo ◽  
Amanda C Fernades

<p>In this study aims to present possibilities for utilization of waste of “Blue Granite Sucuru” obtained in the exploration phase and whose field is disabled, located in the Paraiba Cariri, in the municipality of Sumé, PB. It was determined the physical indices of this material that showed the following values: density 2660 kg / m3 ; porosity and absorption 0.26% 0.10%, and these ratios are consistent with those proposed by NBR 15844 - granites requirements for such coating material. Starting from field visits collect materials from the waste, which were crushed and one hundred selected pieces were measured values of their lengths, thickness and width, analyzed in the light of ISO 9654. The coarse aggregate produced shows high percentage of cubic materials (64%) and 36% elongated / lamellar material. Thus, the use of elongated gravel / lamellar in the manufacture of concrete reduces the strength thereof to increase the porosity and the possibility of segregation of the mortar when the density of the material in ways. Therefore, the crushed rock produced from the material even though they have good resistance to weathering actions on account of their mineralogical composition (low content in minerals iron and magnesium oxides and 60% alkali feldspar) can used in the manufacture of concrete, provided it has precautions as to and grain size to prevent them from becoming trapped between the steel bars that make up the armor and hinder the consolidation of the concrete, which may cause problems such as segregation of the mixture and the empty forms. However these same britas not lend themselves to constitute ballast railways, as have 36% of elongated / lamellar particles when, in use, the maximum allowed is 10%. Therefore, a better economic and environmental feasibility of the blocks which are not used with ornamental purpose is possible, in which the waste can be availed in the form of crushed stone for the construction industry.</p>


2012 ◽  
Vol 519 ◽  
pp. 287-290
Author(s):  
Xiao Bei Wang ◽  
Yuan Hua Lin ◽  
Xu Liang Deng

Porous zirconium dioxide (ZrO2) ceramics has been widely used in biomedicine, heat-insulation and piezoelectric actuators. In this study, a kind of porous ZrO2 ceramics with the gradient porosity and pore sizes was designed to be a composite lamellar material. The porosity and pore size change regularly through the thickness of the layers. This porous lamellar zirconic material has been prepared by the solid state reaction consisting of yttria-stabilized zirconia (YSZ) and stearic acid (SA) powders. The porosity and pore size can be tuned by the addition of SA. The mechanical properties of the graded porous ZrO2 have been studied in detail. The results show that the mechanical characteristics of the gradient porous ZrO2 can be controlled by changing the porosity and pore size.


2006 ◽  
Vol 2006.4 (0) ◽  
pp. 93-94
Author(s):  
Tomohiro SASAKI ◽  
Kaduki SAIKI ◽  
Takao YAKOU ◽  
Shininchi TAKAGI

2005 ◽  
Vol 874 ◽  
Author(s):  
Eve Donnelly ◽  
Rebecca M. Williams ◽  
Shefford P. Baker ◽  
Marjolein C. H. van der Meulen

AbstractCancellous bone plays an important load-bearing role in the skeleton, yet relatively little is known about the microstructure-mechanical property relationships of the tissue at the sub-10 [.proportional]m level. Cancellous tissue is characterized by a layered microstructure with variable proportions of collagen and mineral. The lamellar material is substantially stiffer than the interlamellar material at the nanomechanical level. However, the microstructural origin of the observed differences in mechanical properties of these structures has not been investigated. In this study, second harmonic generation microscopy was used to examine collagen in human vertebral cancellous bone. At the same location in the tissue, nanoindentation was used to assess the indentation modulus of lamellar and interlamellar bone. The stiff lamellae corresponded to areas of highly ordered, collagen-rich material, while the compliant interlamellar regions corresponded to areas of unoriented or collagen-poor material. The lamellar bone was approximately 30% stiffer and contained approximately 50% more oriented collagen than the interlamellar bone. These observed differences in the mechanical properties and collagen content and organization of lamellar and interlamellar tissue are consistent with previous scanning electron microscopy studies showing greater mineral and collagen content and organization in lamellar bone. Given the well-known coupling between collagen and mineral in bone tissue, the mineral distribution may mirror that of the aligned collagen. However, similar measurements of local variations in mineral content are needed to confirm this hypothesis and may provide additional insights into the tissue nanomechanical behavior.


1983 ◽  
Vol 65 (1) ◽  
pp. 85-87 ◽  
Author(s):  
R. N. Sifers ◽  
J. S. Mayes ◽  
R. E. Nordquist

1974 ◽  
Vol 15 (2) ◽  
pp. 379-401
Author(s):  
JOHN. A. KLOETZEL

The ciliate Euplotes is able to expend a very large amount of membrane in the formation of food vacuoles. Calculations based on the rate of ingestion of the food organism Tetrahymena indicate that an amount of food vacuole membrane equivalent to approximately 50-150% of the total Euplotes cell surface area can be produced within 5-10 min. An aggregation of osmiophilic, membrane-limited ‘pharyngeal disks’ is found packed in the cytoplasm just beneath the cell surface membrane in the region of the cell mouth and cytopharynx. These disks, which can be seen also in living cells, have average dimensions of 2 µm diameter by 100 nm thickness, and contain tightly packed layers of a thin lamellar material. Electron micrographs have revealed the apparent fusion of the limiting membrane of disks with the cell's plasma membrane at the base of the gullet. The lamellar disk contents are thereby released to the exterior medium in the buccal cavity, where they form a loosely packed layer over the surface membrane. It is postulated that the pharyngeal disks represent a repository of preformed membrane for use in food vacuole formation. The disk contents may also play a role in food ingestion, although this is not well defined at present. The myeloid content of old food vacuoles is very similar to that of nearby disks in the cytoplasm, suggesting that the disks may form by pinching from shrinking food vacuoles during the digestive cycle. Thus a cycle of membrane flow is envisaged, with the pharyngeal disks (1) coalescing with the surface membrane during food vacuole formation, (2) reforming by pinching from these food vacuoles during digestion, and (3) migrating back to the oral region to serve as a membrane store for subsequent food vacuole formation.


1972 ◽  
Vol 53 (1) ◽  
pp. 185-209 ◽  
Author(s):  
Matthew M. LaVail ◽  
Richard L. Sidman ◽  
Deborah O'Neil

Protein synthesis and displacement in photoreceptor and pigment epithelial cells of inbred normal (Fisher) and mutant (RCS) rats with inherited retinal degeneration has been studied by light and electron microscope radioautography. Groups of animals 14, 15, 17, 19, 27, 35, and 50 days of age were injected with amino acids-H3 and killed at subsequent time intervals. In normal rats, radioactive protein synthesized in the rod inner segments was incorporated into outer segment saccules and displaced outward; the total renewal time of outer segments at all ages was approximately 9 days. In RCS photoreceptors, outer segment displacement was slowed from the normal rate before day 17 and at all subsequent stages. Most of the newly synthesized protein appeared to migrate only into the basal third of the outer segments. Labeling of pigment epithelial cells in RCS rats was always heavier than in controls. Labeled protein was displaced as early as 1 hr postinjection from pigment epithelial cell somas into the apical processes, and by 2 hr postinjection was located in the adjacent lamellar whorls characteristic of the mutant rat retina. After 1 day, radioactivity was present in the 14, 15, 17, and 19 day series of RCS rats in the apical third of the outer segment layer (occupied mainly by extra lamellar material) while there were few silver grains in the middle third of the layer (occupied mainly by distal parts of outer segments). The RCS pigment epithelial cells thus have an unusual synthetic role and appear to be a source of the extra lamellar material. Electron microscope examination revealed that many intact pigment epithelial cell processes were incorporated into the large whorls of extra lamellae. In addition, many disorganized outer segment saccules were observed in continuity with longer membranous lamellae and large lamellar whorls. The extra lamellar material therefore appears to be derived from both rod outer segments and pigment epithelial cells.


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