manganese poisoning
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2019 ◽  
Vol 8 (5) ◽  
pp. 167-171
Author(s):  
Brahmi Mostapha ◽  
Adli Djallal E. H. ◽  
Slimani Miloud ◽  
Arabi Wafaa ◽  
Taibi Narimane ◽  
...  

The mechanisms in the origin of lead and manganese poisoning (Pb-Mn) are multiple, and potentially touch all the body cells. For this purpose, we are interested in oxidative stress induced by Pb-Mn at the erythrocytic level at a dose of 0.2% (Pb) and 4.79 mg/ml (Mn) during the period of gestation and lactation in wistars rats and the ability of mint essential oil, Mentha spicata (MEO) to restore or not this state of stress. The extraction of MEO “HEM” via steam distillation allows us to obtain MEO with an output of 0.49%. Moreo-ver, the analysis of the anti-oxidativeerythrocytic status showed that the co-exposure to Pb-Mn significantly increases enzymes activity of catalase (CAT) and superoxide dismutase (SOD), and significantly reduces the enzyme activity of glutathione peroxidase (GPx), by causing a dysfunction in the anti-oxidative defense system. In contrast, the administration of MEO via intra-peritoneal (IP) during a period of 21 days in the previously Pb-Mn intoxicated rats, that MEO contributes significantly in the improvement of the defenses against radical aggression, through a recovery at the level of anti-oxidative enzymes activities by increasing their ability to eliminate radical compounds.


2018 ◽  
Vol 64 ◽  
pp. 60-69 ◽  
Author(s):  
Yutian Tian ◽  
Shuhan Guo ◽  
Cengceng Chen ◽  
Li Zhao ◽  
Zhen Li ◽  
...  

Toxicology ◽  
2018 ◽  
Vol 410 ◽  
pp. 193-198 ◽  
Author(s):  
Yutian Tian ◽  
Cengceng Chen ◽  
Shuhan Guo ◽  
Li Zhao ◽  
Yongjian Yan

Toxin Reviews ◽  
2016 ◽  
Vol 35 (1-2) ◽  
pp. 38-46
Author(s):  
Tayyebeh Zandevakili ◽  
S. Jamilalddin Fatemi ◽  
Mohammad Shabani ◽  
Khadije Esmaeilpour ◽  
Vahid Sheibani

2009 ◽  
Vol 40 (3) ◽  
pp. 259-268 ◽  
Author(s):  
Salah El Din Abdel Naby ◽  
Khalil Saleh Kayed ◽  
Mohamed Aly Aref

2002 ◽  
Vol 199 (1-2) ◽  
pp. 93-96 ◽  
Author(s):  
Kenjiro Ono ◽  
Kiyonobu Komai ◽  
Masahito Yamada

2000 ◽  
Vol 30 (4) ◽  
Author(s):  
J.A. Neser ◽  
M.A. De Vries ◽  
M. De Vries ◽  
A.J. Van der Merwe ◽  
A.H. Loock ◽  
...  

Author(s):  
J.A. Neser ◽  
M.A. De Vries ◽  
M. De Vries ◽  
A.J. Van der Merwe ◽  
A.H. Loock ◽  
...  
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