BIiochemical Markers in Pregnancy Associated with Sj�gren�s Syndrome and Thrombophilia

Sj�gren�s syndrome (SS) is a multisystemic disease mainly characterized by the hypofunction of the lachrymal and salivary glands and can be either primary or secondary, when related to other autoimmune pathologies. We present the case of a 35-year-old female admitted in the Department of Obstetrics and Gynecology for pregnancy monitoring. The patient had a personal history of a spontaneous abortion one year prior to admission at 5 months of gestation and a maternal history of SS. A multidisciplinary approach with solid obstetrical, rheumatological and neonatal monitoring is essential for best outcomes of the mother and fetus. An early detection of maternal and fetal immune-mediated threats and judicious use of medication is essential in women with autoimmune diseases who plan conceiving.