Outcome of cataract surgery in eyes with uveitis

Purpose: To assess the outcome of cataract surgery in patients with uveitis without the use of prophylactic high dose (> 5-10 mg/day) systemic steroid. Method: A hospital based prospective study enrolling 64 eyes of 60 patients with uveitis and cataract from May 2013 to April 2014 having intraocular inflammation under control for at least 3 months preoperatively and underwent phacoemulsification with in bag placement of foldable acrylic intraocular lens (IOL). Results: Twenty six male and 34 female were included with mean age of 47.23 ± 16.85SD (16-85) years. In 43.75 % of eyes the uveitis was idiopathic followed by sarcoiduveitis (18.7%), Herpetic uveitis (15.6%), Tubercular uveitis (6.2%), VKH (4.6%), HLAB 27(4.6%), Behcet’s, endogenous endophthalmitis, Wegener’s granulomatosis and lepromatous uveitis (1.5% each). Anterior chamber cell count was grade 1+ in 33 eyes (51.56%) on 1st post-operative day and in 29 eyes (45.31%) on second follow up. Out of total 11 eyes (17.18%) that developed fibrin, 7 eyes were treated with subconjunctival injection of dexamethasone with half hourly topical steroid drops. Other 4 eyes that developed fibrin responded to half hourly topical steroid. Dose of oralprednisolone increased in 6 patients in early post operative duration. At the final follow up, 50 eyes (92.58% ) had improvement in best corrected visual acuity and cystoidmacular edema (CME) in 5% (n=3) eyes. Conclusion: Even without the use of preoperative high dose of oral steroid, inflammation was under control with significant improvement in visual acuity 3 months postoperatively.

Herpes Virus Associated Uveitis: Clinical Features, Diagnosis, and Treatment

Herpes viruses are widely disseminated in nature and can be found nearly in all animal spices. They can affect all the structures in the eye causing anterior and posterior uveitis. Clinical features play an important role in the diagnosis but the definite diagnosis is made by the demonstration of intraocular antibody production and the presence of viral DNA in ocular fluids. The advances in molecular diagnostic tests and the rising use of these tests in clinical practice increase the role of these viruses in uveitis etiology. In this article, we aimed to review the clinical features, diagnosis, and treatment protocols of herpetic uveitis.