To study relation between size of ovary and various histomorphological patterns at SRMSIMS

A study which assess the relation between size of ovary and various histomorphological patterns.Gross examination was done carefully examining the outer surface and on-cut surface of ovary, looking for any cyst with its content and type of fluid filled inside, any solid area, papillary projections and growth. Associated tissue piece if received were also carefully examined and grossed.Radiologically, of total 66 non neoplastic cases, 51 are reported as benign ovarian cyst, 05 as complex ovarian cyst, 04 as hemorrhagic cyst, 03 as bulky uterus and 02 as adenexal mass. 03 out of 05 cases of non-specific oophoritis are reported as benign ovarian cyst, all 01 cases of tuberculosis are reported as complex ovarian cyst. Of 07 follicular cysts, 05 are reported as benign ovarian cyst, 01 as complex ovarian cyst and one each as hemorrhagic cyst and bulky uterus. Of 24 cases diagnosed as simple serous cyst histologically, 20 are reported as benign ovarian cyst, 02 as bulky uterus and 02 as adenexal mass. 04 out of 04 cases of endometriosis are reported as benign ovarian cyst. Observational Study. Viable therapeutic administration of ovarian dangerous tumors keeps on being a test to the oncologist. A precise histopathological determination joined with clinical organizing will help in delivering expeditious and fitting treatment to the patient. The ovary is a successive site for essential malignancy. Because of various cell types and its unpredictable design, essential ovarian neoplasms are of different histological types.

Fertility Preservation in Girls with Turner Syndrome: Prognostic Signs of the Presence of Ovarian Follicles

Context: Many girls with Turner syndrome have follicles in their ovaries at adolescence. Objective: Our objective was to study which girls might benefit from ovarian tissue freezing for fertility preservation. Design: Clinical and laboratory parameters and ovarian follicle counts were analyzed among girls referred by 25 pediatric endocrinologists. Subjects and Setting: Fifty-seven girls with Turner syndrome, aged 8–19.8 yr, were studied at a university hospital. Interventions: Ovarian tissue was biopsied laparoscopically, studied for the presence of follicles, and cryopreserved. Blood samples were drawn for hormone measurements. Main Outcome Measures: Presence of follicles in the biopsied tissue related to age, signs of spontaneous puberty, karyotype, and serum concentrations of gonadotropins and anti-Müllerian hormone were assessed. Results: Ovarian biopsy was feasible in 47 of the 57 girls. In 15 of the 57 girls (26%), there were follicles in the tissue piece analyzed histologically. Six of seven girls (86%) with mosaicism, six of 22 (27%) with structural chromosomal abnormalities, and three of 28 with karyotype 45X (10.7%) had follicles. Eight of the 13 girls (62%) with spontaneous menarche had follicles, and 11 of the 19 girls (58%) who had signs of spontaneous puberty had follicles. The age group 12–16 yr had the highest proportion of girls with follicles. Normal FSH and anti-Müllerian hormone concentrations for age and pubertal stage were more frequent in girls with follicles. Conclusions: Signs of spontaneous puberty, mosaicism, and normal hormone concentrations were positive and statistically significant but not exclusive prognostic factors as regards finding follicles.