An Epidemiological Survey of Tongue Lesions in the Oral Pathology Department of Khorasgan Dental School From 2010 to 2020

Background and aims: Many pathologic conditions can affect the tongue and their pattern of occurrence may differ. The objective of this study was the epidemiological survey of tongue lesions reported in a 10-year period in the Oral Pathology Department of Khorasgan Dental School. Methods: In this cross-sectional study, 800 biopsy records were retrieved from the archives of the Oral Pathology Department of Khorasgan Dental School and examined. Moreover, the prevalence of lesions was investigated in terms of age and gender using descriptive statistics. Results: The prevalence of lesions analyzed in the present study was 4.37%. About 71.42% of the participants were female and 28.58% were male. Irritation fibroma had the highest frequency (20%). The most frequent lesion among women was lichen planus with a prevalence of 20% and the most frequent lesion among men was irritation fibroma with a prevalence of 30%. The highest frequency was observed in the age group of 21-30 years. Squamous papilloma, lichen planus, and irritation fibroma were the most common lesions with a prevalence of 25%. No lesion was detected in people aged 1-10 years. Conclusion: In the present study, reactive lesions were the most prevalent tongue lesions. According to the findings, changing the lifestyle and observing oral hygiene seem to help prevent these lesions to a large extent.

Peripheral Ossifying Fibroma: A Case Report

The gingiva is often considered as one of the most common sites of localized growths that are considered to be reactive rather than malignant in nature. Clinically, the majority of these lesions are difficult to identify, and therefore histopathology is useful in diagnosing these lesions as specific entities only on the basis of typical and consistent features. Focal gingival enlargements are quite frequent lesions in the oral cavity amounting to almost 3.1% of all oral tumors and 9.6% of gingival lesions. Peripheral ossifying fibroma (POF) is one of the reactive lesions that have typical histopathological features. Since the late 1940s, intraoral ossifying fibromas have been discussed in the literature. The term “Peripheral ossifying fibroma” is usually used to describe a fibroma of the gingiva which shows areas of calcification or ossification. They are usually classified as non-neoplastic enlargement of the gingiva. Many POFs are thought to develop initially as a pyogenic granuloma that undergoes fibrous maturation and subsequent calcification. However, many authors have suggested that rather than a transitional form of pyogenic granuloma or irritation fibroma, POF represents a separate clinical entity. Different lesions with clinical presentations similar to POF make it difficult to arrive at an appropriate diagnosis. Usually, the treatment of POF includes excision of the lesion surgically with minimal chances of recurrence. This paper describes a case report of a 32 year old female patient who reported growth on gingiva in the mandibular left anterior region of the mouth for three years.

A Multicenter Study of Tongue Lesions from Thailand

Objective Tongue lesions constitute a considerable proportion of the oral lesions. Previous studies on tongue lesions were based on clinical studies. There has been a scarcity of the studies which are based on histopathological examination. This study aimed to determine the prevalence, demographic, and pathologic features of tongue lesions from Thailand. Materials and Methods Biopsy records of the participating institutions were reviewed for lesions on the tongue diagnosed during 1998 to 2017. Demographic data were collected from the biopsy records. Locations were arbitrarily classified as dorsal, lateral, and ventral surfaces, tip of the tongue, and the combination of sites. Lesions of the tongue were classified as reactive/inflammatory, developmental, immune-mediated, cystic, benign, premalignant, malignant, infectious, and miscellaneous categories. Statistical Analysis Data were analyzed by descriptive statistics using SPSS version 20.0. Results Of the 44,188 accessioned cases, 2,153 cases (4.87%) were diagnosed from the tongue. The age of the patients ranged from 3 to 93 years with the mean ± standard deviation = 45.26 ± 20.48 years. The female-to-male ratio was 1.49:1. The majority of the tongue lesions were encountered at the lateral border of the tongue (47.66%). Most of the tongue lesions in the present study (53.74%) fell into the reactive/inflammatory category. Irritation fibroma was the most prevalent lesion (18.99%) followed by squamous cell carcinoma (16.91%), and mucus extravasation phenomenon (14.26%), respectively. Conclusions This study offers new perspective into the study of tongue lesions apart from the clinically based studies. It also demonstrates the difference between the pediatric and the elderly patients. This study provides invaluable database for clinicians when formulating the clinical diagnosis of tongue lesions.

Unusually huge traumatic or irritation fibroma –A case report.

Oral mucosa frequently encounters exophytic growth. Traumatic or irritation fibroma is a benign exophytic oral lesion that develops secondary to tissue.It is the benign reactive lesion, and the treatment of choice is surgical excision.In this case report we present a case of unusually large irritation or traumatic fibroma in left buccal mucosa. Key Words : Taumatic fibroma , Irritation fibroma , Benign tumour , Pedunculated growth

Type 1 and 2 Diabetes Mellitus and Oral Health

Diabetes is characterized by an elevated level of glucose in the blood.Type I diabetes mellitusresults from insulin deficiency. In contrast, type 2 diabetes results of insulin resistance.A third group recently identified confirmed that the secretory defects of gestational insulin are the consequence of abnormal glucose tolerance during pregnancy. Symptoms of diabetes include the classic triad [polyuria, polydipsia, polyphagia]. Long-term complications of diabetes include nephropathy and autoimmune cardiovascular illness dysfunctions. The symptoms of type 2 diabetes develop more slowly than type I diabetes. These patients may be obese. Adults develop micro- and macro- vascular conditions, producing irreversible damages to the eyes (retinopathy, cataracts), kidney (nephropathy), nervous system (neuropathy and parenthesis). Oral complications including candidiasis (fungal infection due to any type of Candida), dental caries, tooth loss, gingivitis, lichen planus, neurosensory disorders (burning mouth syndrome), periodontitis, salivary dysfunction, xerostomia, and taste impairment. Diabetes implicate greater prevalence of fissured tongue, irritation fibroma, traumaticulcers, and recurrent aphthous stomatitis. Hyperglycemia induces non-enzymatic elevated levels of glucose that stimulate interleukin-6 expression. Altogether these factors contribute to cardiovascular disease.