dppc vesicle
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2005 ◽  
Vol 109 (8) ◽  
pp. 3319-3323 ◽  
Author(s):  
Pratik Sen ◽  
Saptarshi Mukherjee ◽  
Amitava Patra ◽  
Kankan Bhattacharyya

2004 ◽  
Vol 18 (2) ◽  
pp. 265-269 ◽  
Author(s):  
Anthony Kennedy ◽  
Carla J. Long ◽  
Peter J. Hmel ◽  
Rickey Hicks ◽  
Thomas J. Reid

The use of dimethylsulfoxide (DMSO) as a cryoprotectant to reduce cellular injury during freezing is well known, however the intermolecular interactions between this amphiphilic molecule and biological membranes that form the basis of this protection are unknown. DMSO–dipalmitoylphosphatidylcholine (DPPC) vesicle interactions were investigated in pulsed-field gradient NMR (PFGNMR) experiments and spectra analysis allowed for the determination of self-diffusion coefficients for each species present. The mole fraction of DMSO associated with the DPPC vesicles was then calculated from the diffusion coefficients: the mole fraction increased from 14% to 42% as the membrane was heated from below to above the main phase transition temperature.


1985 ◽  
Vol 2 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Helmut Sapper ◽  
Klaus-Dieter Roth ◽  
Wolfgang Lohmann

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