anionic spacer
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scholarly journals Enhancing the biological activity of polyoxometalate–peptide nano-fibrils by spacer design

RSC Advances ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 4952-4957
Author(s):  
Valeria Tagliavini ◽  
Claudia Honisch ◽  
Simona Serratì ◽  
Amalia Azzariti ◽  
Marcella Bonchio ◽  
...  
Keyword(s):  
Biological Activity ◽  
Cancer Cell ◽  
Self Assembly ◽  
Cell Targeting ◽  
Cancer Cell Targeting ◽  
Targeting Ability ◽  
Anionic Spacer

The introduction of a tailored hydrophilic/anionic spacer in an Anderson–Evans polyoxometalate, bis-conjugated with demobensin-1 peptide, fosters self-assembly into fibrillary nanostructures and an unprecedented cancer cell targeting ability.

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