Effect of hydrogen sulfide on the characteristics of the neuromuscular synapse terminals of the rat diaphragm

Hydrogen sulfide is one of the gas-transmitters that also performs other biological functions. The antioxidant property of this substance is one of the important ones. The research was conducted on rats of both sexes between 6 and 18 days of age. We have shown that the offspring of females injected subcutaneously with hydrogen sulfide increased the area and luminescence of nerve terminals during postnatal ontogenesis, which can be further used to level the effects of hyperhomocysteinemia on synaptic transmission. Key words: neuromuscular synapse, fluorescent microscopy, hydrogen sulfide.

ECOLOGICAL ASPECTS OF MORPHOGENESIS OF CONNECTIVE TISSUE COMPONENTS OF THE PANCREAS OF A RACCOON DOG IN POSTNATAL ONTOGENESIS OF THE RADIATION FACTOR

There have been no studies devoted to the study of the pancreas of a raccoon dog living in a contaminated area in the world. Therefore, the aim of our research was to study the connective tissue components of the pancreas in a raccoon dog at different stages of postnatal ontogenesis. The material for the study was raccoon dogs seized from former settlements, in the vicinity of lakes Zhartai, Vyura, Gnezdnoye and the Nesvich River in the exclusion zone (30 – kilometer exclusion zone of the Chernobyl nuclear power plant). As a result of the studies, the features of the morphofunctional state of the pancreatic stroma under the influence of the radiation factor were revealed.

FEATURES OF THE PRO-AND ANTIOXIDANT SYSTEM OF CATTLE IN POSTNATAL ONTOGENESIS IN THE BIOGEOCHEMICAL CONDITIONS OF THE ASTRAKHAN REGION

The article presents the results of research on the peculiarities of the functioning of the pro-and antioxidant system of cattle in postnatal ontogenesis in the biogeochemical conditions of the Astrakhan region. The territory of the Astrakhan region is considered to be deficient in the content of selenium in the soil, water and feed, which is confirmed by our research. This is displayed on the body of animals. It was found that the content of selenium in the blood serum is 0.58 mcg/k, which is lower than the physiological value, which leads to the inhibition of the processes of lipid peroxidation in the body of cattle. In the age aspect, the level of diene conjugates and malondialdehyde increases by 7.4-11.4 % and 11.3-16.1 %, respectively. A correlation was established between catalase activity and age (by 19.6% by the 5th year of life). The correlation coefficient is 0.95.

Comparative-morphological analysis of intermuscular nervous plexus book of edilbayevskaya sheep in postnatal ontogenesis

Purpose: To perform a comparative morphological analysis of the intermuscular nerve plexus of the book of the Edilbaev breed sheep in postnatal ontogenesis.Materials and methods. For the experiment, the control and experimental groups were selected in the amount of 35 heads, 5 animals were killed immediately after birth. The rest were divided into control and experimental groups of 5 lambs each. Control groups of lambs were fed naturally on ewes. Experimental groups of lambs, according to the instructions, were on artificial feeding with a sheep milk substitute (ZOM) "Kolvo-Start". The object of histological examination was the ganglia of the book of Edilbaev breed lambs of 4 technological periods: newborns, 15-day-old, 2.5-month-old, 4.5-month-old. We used classical neuromorphological, morphometric and histological methods, as well as processing statistical data.Results. Comparative analysis showed that in the group of medium-sized cells in the ganglia of lambs of 2.5 months of age, there is an intensive growth of the cytoplasm in relation to the nucleus, both in the control and in the experiment. The morphological indicators of the adaptive-compensatory restructuring of the nervous tissue were revealed.Conclusion. The obtained morphometric data from birth to 4.5 months of age testify to the advanced growth of ganglia in the experiment both in length and width, an increase in the linear dimensions of the ganglia of the book occurs. This is due to the pronounced adaptation and formation of the organ in connection with the nature of feeding.