New Forceful Magnetic Bioseparation using GIAMAG Magnet Systems

ABSTRACTMagnetic bioseparation is an important area of biotechnology. Various techniques are used with a wide range of possible applications in bioscience research. Magnetic micro- or nanospheres can be functionalized with appropriate ligands, such as antibodies, with a high affinity to the target, like cells, bacteria or DNA/RNA. In order to realize magnets with efficient separation capabilities, it is important to have a strong force FM acting on the magnetic bodies. FM is proportional to the product of the magnetic field and the field gradient. Many permanent magnets on the market have large magnetic fields, but relatively weak field gradients. GIAMAG magnets have unique and patented designs that produce both very large magnetic fields and high field gradients, resulting in the most forceful magnetic separators available on the market.

Preparation of Magnetic Hybrid Microspheres with Well-Defined Yolk-Shell Structure

A facile and efficient route was reported to prepare a kind of yolk-shell magnetic hybrid microspheres by suspension polymerization and calcinations method. The morphology, structure, and composition of the magnetic microspheres were characterized by FTIR, XRD, TEM, SEM, and TGA analysis. The vibrating-sample magnetometry (VSM) results clearly showed that the magnetic particles were superparamagnetic with saturation magnetization of 32.82 emu/g which makes the microcomposites easily controlled by an external magnetic field. The results revealed that the magnetic hybrid microspheres might have important applications in magnetic bioseparation and drug delivery.