Recent Trifluoromethylation Reactions. A Mini Review Paper

This review highlights recent improvement in trifluoromethylene functionalization processes with CF3 reagents, includes: Togni’s, Umemoto’s, CF3SO2Cl, CF3I, Yagupol’skii-Umemoto, TMSCF3, Langlois (CF3SO2Na) and clarifies the several designing to result the corresponding trifluoromethylated products. In this article, the selective trifluoromethylation reactions with Togni’s reagents and their analogs are detailed, which work transition metals or photoactivated Ru or Ir catalysts as single electron giver to yield CF3 radical intermediate species. This issue is to introduce a draft of diverse reports, presenting the modern reaction collect and mechanics produced during the past five years. This task is demanded by the key protocol connected with the trifluoromethylation reactions, designing to sustain researchers a straight forward understanding of such reactions and to award information for further implements.

Determination of rate constants for trifluoromethyl radical addition to various alkenes via a practical method

A simple method for the determination of CF3-radical addition rate constants to various π-acceptors is introduced.

Reaction of the CF3 Radical with Various Cations (Ar+, Xe+, O2+, NO+, CO2+, C2F5+)

The kinetics of reactions of the trifluoromethyl radical (CF

A mild and fast continuous-flow trifluoromethylation of coumarins with the CF3 radical derived from CF3SO2Na and TBHP

A mild and fast Cu(i)-catalyzed trifluoromethylation of coumarins with CF3SO2Na and TBHP in a continuous-flow reactor has been developed.