Cyclophosphamide Neutralization in Wastewaters Using an Asymmetric Current Density Electrochemical Microreactor

Alkylating antineoplastic agents used in modern oncological treatments constitute noteworthy environmental hazards with a great long-term impact on human health. This paper introduces an asymmetric current density electrochemical microreactor specifically designed to neutralize alkylating cytostatic drugs from wastewaters. The reactor is based on the principle of anodic electro-oxidation (AEO) and on chemical oxidation via anode-generated chlorine reactive species (CRS). The design of this electrochemical reactor facilitates very good (approx. 99%) neutralization yields for the substance used in this study. Keywords: electrochemical reactor, asymmetric current density, cytostatic drug waste, electrooxidation

Efficient Flow Electrochemical Alkoxylation of Pyrrolidine-1-carbaldehyde

We report on the optimization of the alkoxylation of pyrrolidine-1-carbaldehyde by using a new electrochemical microreactor. Precise control of the reaction conditions permits the synthesis of either mono- or dialkoxylated reaction products in high yields.