Rapid Synthesis of Uniform CdSe Nanorods by a Microwave-Assisted Solvothermal Method in Ethylenediamine

A rapid microwave-assisted solvothermal method is reported for the synthesis of uniform CdSe nanorods in ethylenediamine (EDA) using CdCl2 and elemental Se as reactants. The resultant nanorods have a diameter of approximately 10 nm and a length of approximately 300 nm. Our experiments show that the concentrations of EDA and CdCl2 play important roles in product morphology. The well-dispersed CdSe nanorods with high aspect ratios were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray (EDX), UV-vis absorption and photoluminescence (PL).

Procyanidinere therapy of pulmonary fibrosis induced by CdSe nanorods with pulmonary instillation

Background: The CdSe nanorod as a one-dimensional nanostructure has an excellent performance in photoelectric conversion, biological labeling and environmental protection. Thus, it is crucial to investigate its potential adverse health effects at an early stage. Methods: Sprague-Dawley (SD) male rats were exposed to 15 mg/kg CdSe and 200 mg/kg procyanidine (OPC) for 30, 60 and 90 days. Lung tissues were collected on days 30, 60 and 90. Oxidation damages, histopathological analysis, transmission electron microscopy and hydroxyproline level were measured. Results: The lung tissue would be the main target organ after CdSe nanorods entering into biological bodies. Pulmonary instillation of CdSe nanorods could decrease vitality of T-SOD and T-AOC in lung tissues of a rat, increase MDA and hydroxyproline levels and lipid peroxidation products, induce mitochondrial cristae broken and vacuolization, cause inflammatory responses, and finally induce pulmonary fibrosis. The oral administration of procyanidinere could significantly increase the content of antioxidant enzymes, scavenge free radicals, reduce the lipid peroxidation and have protective effects on CdSe nanorods-induced pulmonary fibrosis. Conclusions: CdSe nanorods could induce an extensive inflammatory response, elevate ROS, induce pulmonary fibrosis and reveal time accumulation appearance. OPC has a protective effect on lung injury induced by CdSe nanorods, which might be related to anti-oxidative and anti-inflammatory properties.

Dimensionality-controlled self-assembly of CdSe nanorods into discrete suprastructures within emulsion droplets

Self-assembly of inorganic nanocrystals into ordered superlattices is of particular importance for their application in biomedicine and solid-state optoelectronic devices.