cd68 antigen
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Author(s):  
Ana Velez ◽  
M.D. M.D. ◽  
Ph.D. Ph.D. ◽  
Louis DeJoseph ◽  
M.D. M.D. ◽  
...  

1994 ◽  
Vol 25 (9) ◽  
pp. 872-876 ◽  
Author(s):  
Arif Hameed ◽  
Ralph H. Hruban ◽  
Wes Gage ◽  
George Pettis ◽  
William M. Fox

1994 ◽  
Vol 108 (5) ◽  
pp. 426-430 ◽  
Author(s):  
Giorgio Gherardi ◽  
Cristina Marveggio ◽  
Claudio Cola ◽  
Gianantonio Redaelli

AbstractImmunocytochemistry (ICC) proved to be an essential adjunct in the fine-needle aspiration (FNA) cytological diagnosis of chordoma of the clivus in a 62-year-old woman. The cytological picture in routinely stained smears was not entirely diagnostic for chordoma due to the paucity of typical ‘physalipherous’ cells. To exclude other primary or metastatic neoplasms of the skull base possibly sharing the same cytological picture, additional direct smears were immunostained with antibodies specific for cytokeratin (CK), vimentin (VIM), SI00 protein (SIOOP), carcinoembrionic antigen (CEA), epithelial membrane antigen (EMA), glial fibrillary acidic protein (GFAP), CD68 antigen (KP1) and with the ‘panepithelial’ antibodies B72.3 and Ber-EP4. Chordoma cells showed the following immunoprofile: CK+/VIM−/S100P+/CEA−/EMA+/GFAP−/B72.3−/Ber-EP4−/CD68+. The pattern of immunoreactivity for CK, S100P and CEA confirms previously reported data, while the B72.3−/Ber-EP4−/CD68+ staining profile represents a novel observation. The etection of a CK+/S100+/CEA−/B72.3−/Ber-EP4− immunocytological profile of chordoma cells in aspirates is a basic requirement to exclude pertinent diagnostic differentials, such as metastatic carcinoma, ependymoma and sarcoma, and permits a reliable pre-operative diagnosis of the tumour by aspiration cytology.


1992 ◽  
Vol 55 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Susan G. Elner ◽  
Victor M. Elner ◽  
Jarl C. Nielsen ◽  
Elise Torczynski ◽  
Riley Yu ◽  
...  

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