THE INDICES OF MORBIDITY OF PANCREAS CANCER IN WORKERS OF RADIATION DANGEROUS ENTERPRISE

In Russia, during last decades increasing of morbidity of pancreas cancer is observed. This disease is among leading causes in the structure of mortality of malignant neoplasms. The data concerning effect of ionizing irradiation on development of pancreas cancer is ambiguous. The analysis was carried out concerning indices of morbidity of pancreas cancer in cohort of workers for the first time hired to enterprise of nuclear industry production association «Mayak» in 1948-1982 exposed to prolonged total external gamma-irradiation and internal alpha-irradiation by incorporated plutonium. It is established that in both considered cohort and total population, indices of morbidity of pancreas cancer depended on such non-radiation factors as attained age, gender, calendar period of observation, smoking and value of smoking index, alcohol abuse. The study established increasing of standardized by age indices of morbidity of pancreas cancer in workers exposed to prolonged external gamma-irradiation in doses 0.5 Gy and higher. The effect of internal alpha-irradiation on indices of morbidity of pancreas cancer was absent in examined cohort.