The Target Recovery Strategy for Preventing Avalanche Breakdown on Interdependent Community Networks

Many real infrastructure systems such as power grids and communication networks across cities not only depend on each other but also have community structures. This observation derives a new research subject of the interdependent community networks (ICNs). Recent works showed that the ICNs are extremely vulnerable to the failure of interconnected nodes between communities. Such vulnerability is prone to cause avalanche breakdown of the ICNs. How to improve the robustness of ICNs remains a challenge. In this paper, we propose a new target recovery strategy in the self-awareness recovery model, called recovery strategy based on community structures (RCS). The self-awareness recovery model repairs and reactivates the original pair of failed nodes that belong to mutual boundary of networks during cascading failures. The key insight is that the RCS explicitly considers both intercommunity links and intracommunity links. In this paper, we compare RCS with the state-of-the-art approaches based on randomness, degree centrality, and local centrality. We find that the RCS outperforms the other three strategies on the size of giant component, the existence probability of giant component, the number of iterative cascade steps, and the average degree of the remaining network. Moreover, RCS is robust against a given noise, and the optimal parameter of RCS remains stable even if the recovery ratio varies.

Neurotransplantation Therapy and Cerebellar Reserve

Background & Objective: Neurotransplantation has been recently the focus of interest as a promising therapy to substitute lost cerebellar neurons and improve cerebellar ataxias. However, since cell differentiation and synaptic formation are required to obtain a functional circuitry, highly integrated reproduction of cerebellar anatomy is not a simple process. Rather than a genuine replacement, recent studies have shown that grafted cells rescue surviving cells from neurodegeneration by exerting trophic effects, supporting mitochondrial function, modulating neuroinflammation, stimulating endogenous regenerative processes, and facilitating cerebellar compensatory properties thanks to neural plasticity. On the other hand, accumulating clinical evidence suggests that the self-recovery capacity is still preserved even if the cerebellum is affected by a diffuse and progressive pathology. We put forward the period with intact recovery capacity as “restorable stage” and the notion of reversal capacity as “cerebellar reserve”. Conclusion: The concept of cerebellar reserve is particularly relevant, both theoretically and practically, to target recovery of cerebellar deficits by neurotransplantation. Reinforcing the cerebellar reserve and prolonging the restorable stage can be envisioned as future endpoints of neurotransplantation.

Chemistry and radiochemistry of As, Re and Rh isotopes relevant to radiopharmaceutical applications: high specific activity radionuclides for imaging and treatment

Advances in production, separation, target recovery, and chelation chemistry of high specific activity radionuclides will promote new theranostic agent development.

Integrated sociotherapy – IS from rehabilitation to recovery integrating sociotherapy and cognitivism in a TC for borderline personality disorders

Purpose The purpose of this paper is to explain that an integration of cognitivism with sociotherapy is possible and appropriate to help severe BPD cases. What follows is both an outline and a rationale of this integration. Design/methodology/approach Recovery programs for serious BPD represent a challenge because they require complex answers in three problematic areas: interdependent relationships, emotional intensity and identity, virtually at the same time. This prompted Raymond Gledhill Community the opportunity to integrate recovery programs with treatments that have yielded proven results for each cluster. Schema therapy and Systems Training for Emotional Predictability and Problem Solving have been integrated with sociotherapy. Findings This integration has led to considerable results including: increased motivation among the resident community, the adoption of a shared language, improved communication levels in the community, greater mutual support, increased trust in, and empathy toward, fellow residents, and more self-awareness – even among the facilitators. Originality/value It is the belief that the integration of cognitive tools with sociotherapy can indeed target recovery for people with BPD in a much more efficacious and cost effective manner.