Simultaneous Angiography for the Anterior Segment and Posterior Fundus of Eyes with Anterior Segment Neovascularization using Heidelberg Retina Angiograph 2

Objective: To present a method of indocyanine green angiography (IA) and fluorescein sodium angiography (FA) for simultaneously evaluating anterior segment neovascularization and fundus abnormality.Participants: We examined 19 eyes of 19 patients suspected of having neovascularization in the anterior segment of the eye. Seventeen eyes of 17 patients suffered from proliferative diabetic retinopathy, and two eyes of 2 patients had central retinal vein occlusion.Methods: Using Heidelberg Retina Angiograph 2 (HRA2), we performed angiography of the anterior and posterior segment of the eye.Results: Of the 19 cases, anterior segment neovascularization was clearly observed with slit-lamp examination and gonioscopy in 12 eyes (63.1%). However, anterior segment neovascularization was detected by HRA2 angiography in 18 eyes (94.7%). Posterior segment angiography revealed non-perfusion area in 16 eyes (84.2%) and retinal neovascularization in 10 eyes (52.6%). In one case, the posterior segment findings were not obtained due to vitreous hemorrhaging.Conclusion: Simultaneous anterior and posterior segment HRA2 angiography using indocyanine green andfluorescein sodium is a useful technique for detecting neovascularization in the anterior segment of the eye as well as non-perfusion areas and neovascularization of the retina.

Registration and Fusion of the Autofluorescent and Infrared Retinal Images

This article deals with registration and fusion of multimodal opththalmologic images obtained by means of a laser scanning device (Heidelberg retina angiograph). The registration framework has been designed and tested for combination of autofluorescent and infrared images. This process is a necessary step for consecutive pixel level fusion and analysis utilizing information from both modalities. Two fusion methods are presented and compared.