bovine small intestine
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2001 ◽  
Vol 130-132 ◽  
pp. 609-615
Author(s):  
Tadashi Mizoguchi ◽  
Isamu Maeda ◽  
Kiyohito Yagi ◽  
Peter F. Kador

1999 ◽  
Vol 276 (6) ◽  
pp. G1442-G1451
Author(s):  
John P. Cant ◽  
Paul H. Luimes ◽  
Tom C. Wright ◽  
Brian W. McBride

To test the hypothesis that the uptake capacity of the bovine small intestine for glucose is upregulated to match or slightly exceed glucose delivery, glucose was continuously infused into the proximal duodenum of four cannulated holstein heifers. Every 3 days, infusion rates were increased by an average of 34 mmol/h. A model of glucose disappearance from multiple boluses of intestinal digesta was used to estimate the transporter maximum velocity and functional maximum uptake capacity for the entire small intestine from average ileal glucose flows during the third day of each period. Because of its intermittency, digesta flow remained independent of simulated transit time. For each unit increase in glucose infusion rate, uptake capacity increased by only 0.55 units. Excess capacity for glucose uptake was approximately twofold in forage-fed cattle and declined to below delivery at infusions of >208 mmol/h added glucose, approximately three times the normal load. Calculations for cattle, sheep, and rats indicate that the glucose transport capacity of the small intestine is typically underutilized because of a fraction of time that transporters are not in contact with digesta.


1992 ◽  
Vol 298 (2) ◽  
pp. 486-491 ◽  
Author(s):  
Hajime Takikawa ◽  
Sakiko Arai ◽  
Masami Yamanaka

1989 ◽  
Vol 25 (4) ◽  
pp. 365-372 ◽  
Author(s):  
Naommy Takahashi ◽  
Hirokazu Kumanaka ◽  
Hideo Takagi ◽  
Nobuko Mori

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