human pk prediction
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A Novel Experimental and Theoretical Method for Estimating Albumin-Mediated Hepatic Uptake Based on the Albumin Binding Fraction in Plasma and Human PK Prediction Using a Physiologically-Based Pharmacokinetic Approach

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.01.015 ◽

2021 ◽

Author(s):

Yu Egashira ◽

Tomoka Shimada ◽

Kei Mayumi

Keyword(s):

Theoretical Method ◽

Hepatic Uptake ◽

Albumin Binding ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Approach ◽

Human Pk Prediction

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A novel physiologically based pharmacokinetics (PBPK) approach for human PK prediction

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2017.11.280 ◽

2018 ◽

Vol 33 (1) ◽

pp. S85-S86

Author(s):

Kei Mayumi ◽

Takanobu Matsuzaki ◽

Satoko Funaki ◽

Shingo Sakamoto ◽

Shuichi Ohnishi ◽

...

Keyword(s):

Physiologically Based Pharmacokinetics ◽

Physiologically Based ◽

Human Pk Prediction

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Human PK Prediction and Modeling

Comprehensive Medicinal Chemistry III ◽

10.1016/b978-0-12-409547-2.12373-x ◽

2017 ◽

pp. 51-82

Author(s):

T.H. Grasela ◽

V. Lukacova ◽

D.N. Morris ◽

R.D. Clark ◽

K.A. Andrews ◽

...

Keyword(s):

Human Pk Prediction

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Drug Design Tools - In Silico, In Vitro and In Vivo ADME/PK Prediction and Interpretation: Is PK in Monkey An Essential Part of a Good Human PK Prediction?

Current Topics in Medicinal Chemistry ◽

10.2174/156802611794480954 ◽

2011 ◽

Vol 11 (4) ◽

pp. 351-357 ◽

Cited By ~ 6

Author(s):

Natilie A. Hosea

Keyword(s):

Drug Design ◽

In Silico ◽

Design Tools ◽

Human Pk Prediction

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Evaluate human PK prediction of compound LY based on allometric scaling with three species

Clinical Pharmacology & Therapeutics ◽

10.1016/j.clpt.2003.11.114 ◽

2004 ◽

Vol 75 (2) ◽

pp. P30 ◽

Cited By ~ 1

Author(s):

S Mu

Keyword(s):

Allometric Scaling ◽

Human Pk Prediction

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