Enantioselective [3 + 2] cycloaddition and rearrangement of thiazolium salts to synthesize thiazole and 1,4-thiazine derivatives

A highly efficient catalytic asymmetric [3 + 2] cycloaddition/rearrangement cascade of thiazolium N-ylides with various electron-deficient 2-π components was achieved, providing a convenient method to access hydropyrrolo-thiazole and hydropyrrolo-thiazine derivatives.

Cascade bicyclizations of o-alkynyl aldehydes with thiazolium salts: a new access toward poly-functionalized indeno[2,1-b]pyrroles

A new cascade bicyclization of o-alkynyl aldehydes with thiazolium salts is described, in which 25 examples of densely functionalized indeno[2,1-b]pyrroles are achieved in a functional-group-compatible manner.