intrauterine closure
Recently Published Documents


TOTAL DOCUMENTS

14
(FIVE YEARS 0)

H-INDEX

7
(FIVE YEARS 0)

Author(s):  
Vijay K. Gavade ◽  
Ravindra S. Pawar ◽  
Uday S. Patil ◽  
Sandeep M ◽  
Prabhu Teja M

Spontaneous premature closure of the human fetal ductus arteriosus is an uncommon event that often results in significant morbidity and mortality. We present a case of a neonate with prenatal previously not detected intrauterine closure of the ductus arteriosus in a 21-year-old ,G3P1A2L1 mother with type 2 consanguinity at 39 weeks of gestation, with previous scans showing placenta previa grade 1 at  21weeks and Doppler study showing  pericardial effusion at 36weeks.Caesarean section was performed in view of absent progression of labour. A male newborn weighing 4100gm, required bag and mask and intubation. With an excellent neonatal outcome. Finally we suggest that fetal echo in third trimester & maternal education programs to avoid  self-medication and provide training for good diet is necessary.


2019 ◽  
Vol 24 (2) ◽  
pp. 115-119
Author(s):  
Nishit Mummareddy ◽  
Michael C. Dewan ◽  
Anna Huang ◽  
Jade Basem ◽  
Kelly A. Bennett ◽  
...  

OBJECTIVEThe Management of Myelomeningocele Study (MOMS) established several important benefits of myelomeningocele fetal closure, including decreased need for shunting at 30 months. However, the effects of fetal closure on long-term quality of life (QOL) have not been studied. In this study, the authors aimed to analyze the differences in long-term QOL between children treated with intrauterine repair and those treated with postnatal repair.METHODSCaregivers of children treated with either intrauterine or postnatal closure at a tertiary acute care hospital between 1997 and 2003 were contacted to participate. The Pediatric Quality of Life Inventory (PedsQL 4.0) and a surgical history questionnaire were administered over the phone. Responses to the QOL survey were reverse scored and linearly transformed to a 0–100 scale, with a higher score indicating better QOL. The Mann-Whitney U-test was used to analyze differences in means.RESULTSSeventy-four children had MMC repair between 1997 and 2003. Twenty-three (31%) of the patients’ families responded to the PedsQL 4.0 questionnaire. Of these 23 children, 11 had intrauterine closure and 12 had postnatal closure. The intrauterine group did not differ in age (median [IQR] 17 years [14–17 years] vs 15 years [14–19 years], p = 0.926), sex (27.3% vs 41.7% male, p = 0.469), or lesion level (p = 0.199) from the postnatal group. Fewer patients in the intrauterine group underwent neurosurgical procedures than those in the postnatal group (55.6% vs 100%, p = 0.018). However, of the children receiving neurosurgical procedures, there was no difference in the number of procedures between the intrauterine and postnatal groups (median [IQR] 4 [2–10.5] vs 2.5 [1.75–6.25], p = 0.458). There was no difference in the percentage of children receiving nonneurosurgical procedures between the two groups (100% vs 100%, p > 0.99). Children who underwent intrauterine closure had significantly higher psychosocial health (median [IQR] 70.0 [56.7–83.3] vs 55.0 [42.1–60.0], p = 0.015) as well as total QOL (median [IQR] 56.5 [55.4–81.5] vs 49.5 [32.9–59.0], p = 0.019) than children with postnatal closure. Physical health was not significantly different between the two groups (median [IQR] 62.5 [37.5–78.1] vs 39.1 [18.8–59.4], p = 0.108).CONCLUSIONSRelative to postnatal closure, children who underwent intrauterine closure of MMC demonstrated better long-term QOL as measured by psychosocial and overall QOL metrics. Given that not all medical and socioeconomic confounders were adjusted for due to the low sample size, validation of these results in a larger population and across multiple centers is needed.


2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Cailly Howell-McLean ◽  
Andrea Scheurer-Monaghan

Abstract Intrauterine closure of the ductus arteriosus is an abnormal occurrence with significant consequences for delivery and neonatal outcomes. We describe a case of intrauterine closure of the ductus arteriosus resulting in non-immune hydrops.


2014 ◽  
Vol 45 (6) ◽  
pp. 936-940 ◽  
Author(s):  
Tomas Dobrocky ◽  
Lukas Ebner ◽  
Benjamin Liniger ◽  
Christian Weisstanner ◽  
Enno Stranzinger
Keyword(s):  

2004 ◽  
Vol 16 (2) ◽  
pp. 1-4 ◽  
Author(s):  
Noel Tulipan

Preliminary evidence suggests that intrauterine myelomeningocele repair may benefit patients by reducing the both incidence of hydrocephalus and the severity of the Chiari malformation; however, this benefit remains unproved. Furthermore, the procedure entails substantial risks not associated with conventional therapy. A randomized controlled trial of intrauterine and conventional therapies is underway. This study should definitively establish the procedure-related risks and benefits. Regardless of the outcome, it is clear that the risks of intrauterine intervention need to be reduced before myelomeningocele, or other congenital malformations, can be effectively treated prior to birth. To that end, studies are being conducted to assess the potential advantages of applying state-of-the-art endoscopic techniques to intrauterine therapy. If benefit can be proven and risks reduced, intrauterine myelomeningocele repair has the potential to become the preferred therapy for patients suffering from this debilitating disease.


2000 ◽  
Vol 32 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Kyle J. Mangels ◽  
Noel Tulipan ◽  
Joseph P. Bruner ◽  
Delia Nickolaus

Sign in / Sign up

Export Citation Format

Share Document