chain separation
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2014 ◽  
Author(s):  
James Hanna ◽  
Wesley Royston ◽  
Rick Warner

2008 ◽  
Vol 32 (6) ◽  
pp. 951-954 ◽  
Author(s):  
Zhao Bin ◽  
He Jingzhen ◽  
Wang Daocai ◽  
Liu Kai ◽  
Liu Cheng

2008 ◽  
Vol 36 (4) ◽  
pp. 712-716 ◽  
Author(s):  
Victoria A. Doronina ◽  
Pablo de Felipe ◽  
Cheng Wu ◽  
Pamila Sharma ◽  
Matthew S. Sachs ◽  
...  

Some RNA and protein sequences are capable of directing changes to the course of translation from that expected from the mRNA sequence, and this process is termed translational ‘recoding’. ‘CHYSEL’ peptides are ∼19-amino-acid sequences found in many viral genomes. When translated at internal portions of polypeptides, they yield co-translational separation of the nascent chain at their C-termini. We dissected the reaction promoted by CHYSEL sequences using yeast genetics and in vitro translation systems. Our results indicate that the reaction occurs within the peptidyltransferase centre of the ribosome where the nascent chain is hydrolytically released from tRNA despite the presence of further sense codons.


1998 ◽  
Vol 19 (10) ◽  
pp. 1733-1737 ◽  
Author(s):  
Pier Giorgio Righetti ◽  
Arianna Saccomani ◽  
Alexander V. Stoyanov ◽  
Cecilia Gelfi

1985 ◽  
Vol 4 (10) ◽  
pp. 2539-2545 ◽  
Author(s):  
P. Johnson ◽  
J. Gagnon ◽  
A.N. Barclay ◽  
A.F. Williams

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