Giant hysteromyoma after vaginoplasty in a woman with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome: case report and review of the literature

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital disorder characterized by congenital absence of both the uterus and vagina. Some patients require surgery to create a neovagina, however, the preservation of a nonfunctional rudimentary uterus after surgery may lead to long-term complications. Herein, a rare case of a giant hysteromyoma after vaginoplasty, in a 31-year-old Chinese female patient who was diagnosed with MRKH syndrome, is reported. The patient, who had undergone vaginal reconstruction 4 years previously, presented with abdominal distension for the previous 2 weeks. Transabdominal ultrasonography showed a firm mass of approximately 10 × 10 cm in the lower abdomen. The patient subsequently underwent an exploratory laparotomy, and a leiomyoma from her rudimentary uterus was removed. Beside this case, seven cases, published between 2004 and 2020, were identified during a literature search. Findings of the present and previously published cases suggest that gynaecologists should pay particular attention to the risks of pelvic complications in female patients with MRKH syndrome who have previously undergone surgery, and select appropriate therapeutic methods.

Comprehensive Approach to Rehabilitation of Women with Postradiation Complications as a Result of Prior Endometrial Cancer (Case Report)

Objective of the Paper: To assess the efficiency of a comprehensive approach to the management of pelvic postradiation complications in women. Key Points. Pelvic damages from radiation (postradiation proctitis, cystitis, urethritis) are the most common complications following pelvic radiation in women. According to various authors, the rate of late pelvic complications can reach 30%. A third of survivors are diagnosed with a new disease, which significantly deteriorates the quality of life and required long-lasting therapy. The article describes a case report of successful therapy in a patient with postradiation pelvic complications. Conclusion. The conservative treatment of postradiation pelvic complications makes it possible to improve the quality of patients’ life, especially if initiated immediately after surgery and radiation. The most efficient mode is a combination of local, drug and physical therapy. Keywords: postradiation cystitis, endometrial cancer, rehabilitation of endometrial cancer survivors, ammonium dermatitis, Ingaron