Исследование механических характеристик нативных фибробластов с помощью атомно-силового микроскопа

It was found that living fibroblasts become more rigid after exposure to colchicine. For reliable measurements, we identified the cells, that during indentation interact with weak lateral forces that do not distort the normal force contribution. The atomic force microscopy data of the mechanical characteristics of such cells are interpreted unambiguously.