The basics of radiation protection in theatre for the patient follow principles similar to those used in plain-film imaging. These include ensuring positive identification of the patient, justification of radiation exposure, avoiding irradiation of pregnant patients wherever possible, minimization and optimization of exposures performed (ALARP principle), protection of all staff involved, and recording and monitoring of all exposures performed. This chapter covers the aspects of protection from radiation for the patient, surgical team, and the radiographer when performing imaging during surgical interventions. Topics covered include the use of beam collimation, minimizing exposure to the patient and team, radiation scatter, and the use and requirements of radiation shielding such as lead aprons and barriers.