elastic plcl
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Soft Matter ◽  
2020 ◽  
Vol 16 (8) ◽  
pp. 2141-2148 ◽  
Author(s):  
Wenshuai Liu ◽  
Zujian Feng ◽  
Wenbin Ou-Yang ◽  
Xiangbin Pan ◽  
Xiaoli Wang ◽  
...  

Implantable PLCL scaffolds with designed architectures, tunable elasticity and good biocompatibility were manufactured by 3D printing.


2011 ◽  
Vol 19 (2) ◽  
pp. 122-129 ◽  
Author(s):  
Kavitha Hassan ◽  
Sang Hoon Kim ◽  
Insu Park ◽  
Sun Hee Lee ◽  
Su Hee Kim ◽  
...  

2008 ◽  
Vol 30 (12) ◽  
pp. 2085-2090 ◽  
Author(s):  
Jin Ik Lim ◽  
Bin Yu ◽  
Yong-Keun Lee

2007 ◽  
Vol 342-343 ◽  
pp. 405-408
Author(s):  
Young Mee Jung ◽  
Soo Hyun Kim ◽  
Sang Heon Kim ◽  
Young Ha Kim ◽  
Byoung Goo Min

Mechano-active scaffolds were fabricated from very elastic poly(L-lactide-co-ε-carprolactone). The scaffolds with 80 % porosity and 300~500 μm pore size were prepared by a gel-pressing method. As a control group for elastic properties of polymer scaffolds, rigid poly L-lactide scaffolds were fabricated. The scaffolds were seeded with chondrocytes and cultured to evaluate the effect of elastic properties of polymer scaffolds for the differentiation and the ECM secretion of chondrocytes. Also, the chondrocytes-seeded constructs were implanted in nude mice subcutaneously to investigate their biocompatibility and cartilage formation. From the biochemical analyses, chondrogenic differentiation was sustained and enhanced significantly and chondral extracellular matrix was increased through mechanical stimulation of dynamic environment in the dynamic body systems. Histological analysis showed that implants of PLCL constructs formed mature and well-developed cartilaginous tissue, as evidenced by chondrocytes within lacunae. Consequently, the elastic PLCL scaffolds could be used to engineer cartilage in mechanically dynamic environments


Biomaterials ◽  
2005 ◽  
Vol 26 (12) ◽  
pp. 1405-1411 ◽  
Author(s):  
Sung In Jeong ◽  
Jae Hyun Kwon ◽  
Jin Ik Lim ◽  
Seung-Woo Cho ◽  
Youngmee Jung ◽  
...  

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