e14112 Background: Our group is interested in designing and programming social robots that augment our staff capabilities in performing different cognitive tasks in the clinic. This study examined patients' interest and comfort with various robot form factors, when screened for distress as part of a routine patient evaluation. Methods: 199 Patients (N) (Power > .80) were presented 7 commercially available robot forms and rated their comfort and interest in interacting with each one on a 5-point Likert scale (1 = Strongly Agree, 3 = Neutral, 5 = Strongly disagree).One sample t-tests compared the difference between the overall mean ratings and neutral point for comfort and interest. Independent samples t-test examined sex differences in overall ratings. Robust ANOVAs and post-hoc tests compared ratings across forms. Results: Results indicated significant interest and comfort in interacting with any robot tested, with men more interested and comfortable (see Table). Robust ANOVA indicated significant main effects for robot type ( Qcomfort = 31 .12; Qinteraction = 26 .52 , ps < .005) and sex ( Qcomfort = 21 .74; Qinteraction = 19 .35 , ps < .005) on comfort and interest. Post-hoc tests indicated that taller and narrower robots were least favored; however, there was no clear preferred form. Conclusions: Our findings suggest that patients are comfortable and interested in interacting with a robot, with men more comfortable and interested. Across robot forms, the taller and narrower forms were less favorable to patients. Future implementations of robotic interfaces may wish to avoid taller and narrower form factors. These data have informed the current model being tested in our clinics, which will be available for display. [Table: see text]