Correction: Tridentate tripodal sulfur ligand as a stable molecular surface anchor for the fabrication of oligonucleotide-gold based label-free biosensors

Correction for ‘Tridentate tripodal sulfur ligand as a stable molecular surface anchor for the fabrication of oligonucleotide-gold based label-free biosensors’ by Huancai Yin et al., Anal. Methods, 2017, 9, 600–608.

Tridentate tripodal sulfur ligand as a stable molecular surface anchor for the fabrication of oligonucleotide-gold based label-free biosensors

The syntheses of a novel tripodal surface anchor, 2,4,9-trithiaadamantane, are reported.

Synthesis of a labile sulfur-centred ligand, [S(H)C(PPh2S)2]−: structural diversity in lithium(i), zinc(ii) and nickel(ii) complexes

Structural isomerism: formation of a labile tridentate sulfur-ligand led to the isolation of the first examples of Ohand SP Ni(ii) isomers of the same ligand in [Ni{S(H)C(PPh2S)2}2] and their fluxional behaviour is examined.

Construction of a porous three dimensional rare earth metal–sulfur–ligand open framework

By using piperazine-1,4-dicarbodithiolate (pipzdtc2−) as the organic linker and the Nd3+ cation as the inorganic motif, a 3D rare earth metal–sulfur–ligand MOF with one-dimensional channels was obtained.

Molybdenum and tungsten oxidoreductase model chemistry

After introducing the general topic of molybdenum and tungsten dependent oxidoreductases[1] our group's strategic approaches relating to issues posed by the structures and functions of these enzymes' cofactors will be presented. Cofactor related questions will be discussed in detail which, at least to some extent, could be answered by model synthesis and crystallographic plus spectroscopic and/or electrochemical evaluation. These are in particular the influence, the type of coordination to the peptide may have on the catalytic performance, the choice of metal (molybdeum versus tungsten) in these enzymes and the respective evolutionary change in preference.[2,3] Finally some exciting and entirly unanticipated crystallographic discoveries will be presented.These are for instance unusual binding motifs, coordination polymer structures, hydrogen bonding and additional non-covalent interactions between dithiolene sulfur ligand atoms and potassium and sodium counter ions.

Cisplatin-related drugs for nongenomic targets: Forcing the reactivity with nucleobases

The products obtained by forcing the reaction with nucleosides (guanosine, Guo, and adenosine, Ado) of potential anticancer drugs for nongenomic targets [PtCl(O,O'-acac)(L)] (L = dimethyl sulfoxide, DMSO; dimethyl sulfide, DMS), closely related to their very powerful organometallic analogues [Pt(O,O'-acac)(γ-acac)(L)], have been studied. [PtCl(O,O'-acac)(L)] and [Pt(O,O'-acac)(γ-acac)(L)] complexes were reported unreactive toward nucleobases. Aquo species [Pt(O,O'-acac)H2O(L)]+, obtained from [PtCl(O,O'-acac)(L)] by Ag+ driven coordinated Cl– removal, gave access to [Pt(O,O'-acac)(L)(nucleoside)]+ ([Pt(O,O'-acac)(DMSO)(Guo)]+, [Pt(O,O'-acac)(DMS)(Guo)]+, [Pt(O,O'-acac)(DMSO)(Ado)]+). The effect of the chelate oxygen donor acac (with respect to a chelate diammine), the role of the sulfur ligand (DMSO, DMS), and the influence of the purinic nucleoside itself on the coordinated Guo or Ado dynamic motions in [Pt(O,O'-acac)(L)(nucleoside)]+ complexes have been investigated by NMR spectroscopy. Interestingly, a slow rotation of nucleobase around the Pt–N(7) bond with formation of two rotamers was observed already at room temperature only in the case of [Pt(O,O'-acac)(DMSO)(Guo)]+. On the other hand, no hindered rotation at room temperature was detected in the analogous [Pt(O,O'-acac)(DMS)(Guo)]+ and [Pt(O,O'-acac)(DMSO)(Ado)]+ complexes. Data suggest that rotation of the nucleoside in [Pt(O,O'-acac)(L)(nucleoside)]+ is very different with respect to the analogous [Pt(diammine)(L)(nucleoside)]2+ systems, due to specific interactions between the acac chelate ligand, the DMSO, and the nucleobase.