Male-mediated maturation in a wild primate

In humans, a controversial hypothesis suggests that father absence promotes early puberty in daughters. Data from rodents confirm females accelerate maturation with exposure to novel males (“Vandenbergh effect”) and delay it with exposure to male relatives. Here, we report the first case of male-mediated maturation in a wild primate, geladas (Theropithecus gelada). Females were more likely to mature after a change in the reproductive male: some matured earlier than expected (Vandenbergh effect) and some later (due to father presence). Novel males stimulated a surge in estrogens for all immature females - even females too young to mature. Although male-mediated puberty accelerated first births, the effect was modest, suggesting that alternative scenarios, such as co-evolution with the Bruce effect (male-mediated fetal loss) may explain this phenomenon.One Sentence SummaryNovel males induce an estrogen surge, male-mediated puberty, and a head-start on reproduction for immature female geladas.

Unexplained Repeated Pregnancy Loss is Associated with Altered Perceptual and Brain Responses to Men’s Body-Odor

ABSTRACTIn the Bruce effect, pregnant mice remember the odor of the fathering male, and miscarry in response to the odor of a male stranger. Humans experience a high rate of unexplained spontaneous miscarriage. Could it be that a portion of these miscarriages reflect a Bruce-like effect? Given ethical constraints on a direct test, we instead probed for circumstantial evidence in women with repeated pregnancy loss (RPL). Consistent with a Bruce-like effect, women with RPL remembered the body-odor of their spouse, but controls could not. Also consistent with a Bruce-like effect, body-odor from a stranger man caused increased activity in the hypothalamus of women experiencing RPL, yet decreased activity in the hypothalamus of women controls. Finally, RPL was associated with reduced olfactory-bulb volume. Although not causal, these observations link RPL with an altered behavioral and brain response to men’s body-odor, implicating the olfactory system in this poorly understood or managed condition.

Data quality and the comparative method: the case of pregnancy failure in rodents

In mammalian species where infanticide by males is likely, females exhibit counterstrategies to prevent or mitigate the costs of infanticide. One putative mitigation strategy is the “Bruce effect,” in which pregnant or inseminated females exposed to an unfamiliar male experience pregnancy block or failure. Females then mate with the new male, thus shifting investment from a “doomed” pregnancy to a more fruitful one. However, the Bruce effect may be an adaptive response to other factors besides infanticide. For example, if paternal care is necessary for offspring survival, and an unfamiliar male replacing the original mate is unlikely to provide such care to offspring of a litter it did not sire, then a female may terminate a pregnancy to initiate a new one. The infanticide and paternal care hypotheses have not been rigorously tested because comparative data on the Bruce effect across mammals are scarce. We compiled data on the Bruce effect, infanticide, and paternal care from one particularly rich source of information, rodents, but found the data set to be less rich than expected. The Bruce effect, infanticide, and paternal care were common among rodent species, but we found no clear relationship among the traits. However, this was likely due to 1) a bias toward positive results, 2) missing data, and 3) a reliance on studies of captive animals. These are common problems in comparative research, and we outline standards that should be implemented to successfully answer questions of importance in the field.

The ‘Woman in Red’ effect: pipefish males curb pregnancies at the sight of an attractive female

In an old Gene Wilder movie, an attractive woman dressed in red devastated a man's current relationship. We have found a similar ‘Woman in Red’ effect in pipefish, a group of fish where pregnancy occurs in males. We tested for the existence of pregnancy blocks in pregnant male black-striped pipefish ( Syngnathus abaster ). We allowed pregnant males to see females that were larger and even more attractive than their original high-quality mates and monitored the survival and growth of developing offspring. After exposure to these extremely attractive females, males produced smaller offspring in more heterogeneous broods and showed a higher rate of spontaneous offspring abortion. Although we did not observe a full pregnancy block, our results show that males are able to reduce investment in current broods when faced with prospects of a more successful future reproduction with a potentially better mate. This ‘Woman in Red’ life-history trade-off between present and future reproduction has similarities to the Bruce effect, and our study represents, to our knowledge, the first documentation of such a phenomenon outside mammals.

Twinning in Norway Following the Oslo Massacre: Evidence of a ‘Bruce Effect’ in Humans

Emerging theory and empirical work suggest that the ‘Bruce Effect’, or the increase in spontaneous abortion observed in non-human species when environments become threatening to offspring survival, may also appear in humans. We argue that, if it does, the effect would appear in the odds of twins among male and female live births. We test the hypothesis, implied by our argument, that the odds of a twin among male infants in Norway fell below, while those among females rose above, expected levels among birth cohorts in gestation in July 2011 when a deranged man murdered 77 Norwegians, including many youths. Results support the hypothesis and imply that the Bruce Effect operates in women to autonomically raise the standard of fetal fitness necessary to extend the gestation of twins. This circumstance has implications for using twins to estimate the relative contributions of genes and environment to human responses to exogenous stimuli.