Pilot plant tests to demonstrate the functionality of sealing elements made of salt cut bricks

The long-term safe containment of high-level radioactive waste in a repository in rock salt is ensured if the geological barriers in conjunction with the geotechnical barriers are permanently impermeable to fluids. As such, an essential factor in underground disposal is to confirm that the interfaces between the biosphere and the lithosphere, i.e., shafts, boreholes, and galleries, created during the excavation of underground cavities can be sufficiently tightly sealed. An essential element of the sealing system required to this end is shaft closure. All shaft closure concepts developed thus far include sealing and supporting elements in repository shafts, but differ in the arrangement of these structural elements and the materials used. The materials currently proposed and planned for the construction of the sealing elements include: clay/bentonite, asphalt/bitumen, crushed salt, and salt/sorel cement. In addition to the materials mentioned above, a research project funded by the German Federal Ministry for Economic Affairs and Energy (Bundesministerium für Wirtschaft und Energie, BMWi) is investigating the possibility of integrating a layer of salt cut bricks several decameters to 100 m thick into the shaft closure system as a sealing element that provides the option of allowing the geological barrier to heal in the long term. Like the surrounding rock mass, the salt cut bricks are made of natural rock salt. According to this plan, the profile of the bricks is designed to minimize joint volume as far as possible by cutting them to match the geometry of the shaft. The joints between the salt cut bricks can either be filled with, for example, a supersaturated salt solution, Magnesium building materials, molten salt, crushed salt, etc., or directly brought into contact by wetting the surface of the salt cut bricks. Once the salt solution has hardened (cooling of the solution, evaporation of the mixing water), only the pore space in the crushed-salt joint sealant filled with salt solution or air, or the joint volume resulting from the mismatch between individual rock salt bricks are susceptible to a reaction. This means that the sealing element consisting of salt cut bricks develops early supporting pressure against the creeping rock salt of the rock mass compared to crushed salt, has a low initial porosity and already shows a strong sealing effect in the short term (regression of the loosened zone). One can also assume that cohesive bonding between the surrounding rock and the sealing element can already be achieved by introducing the joint filling or by wetting the contact surfaces of the salt cut bricks (no or reduced separation planes in the contact zone). Essential prerequisites for the investigation of the geomechanical-geohydraulic effectiveness of a sealing element made of salt cut bricks included the development and construction of a pilot plant to analyze the mechanical and hydraulic material properties of the bonding system comprising salt cut bricks and joint sealing (FKZ 02E11223, FKZ 02E11425), as well as preliminary investigations on the production of salt cut bricks and joint sealant (→ cutting technique/processing of salt cut bricks; maufacture/workability of jointing material) and on the spatial arrangement of the salt cut bricks (→ avoidance of continuous axial joints in the bonding system, Fig. 1). The presentation includes the results of the research work on the development, construction and commissioning of the pilot plant, as well as the first successful test results demonstrating the functionality of sealing elements made of salt cut bricks.

Surgical Approach in Calves with Omphalitis

Background:Pathological changes in the umbilical region are common in calves. Among such alterations, omphalitis is included. This term is used to define inflammation and infection of the external structures of the umbilicus. According to the affected structures, it can be subclassified into omphalophlebitis, omphaloarteritis, omphalourachitis and panvasculitis. These inflammations are usually associated with bacterial infections. There are predisposing conditions that include inadequate handling such as poor hygiene and neglect of primary care. Omphalitis can affect the animal in a multisystemic way, compromising its well-being and bringing economic losses. In treatment, the use of antimicrobials does not always solve the problem. Thus, surgical treatment can be used, which has good results and should be the choice in the disease. The objective of this work is to report 30 cases of omphalitis in calves, submitted to surgical or conservative treatment.Materials, Methods & Results: Thirty cases of omphalitis in calves treated in the routine of the Veterinary Hospital of the Paranaense University was analyzed. On physical examination, the animals presented fever, apathy, hyporexia or anorexia and increase of umbilical volume, usually with purulent secretion. Some animals had sepsis and arthritis. In animals with sepsis, hyperemia of the episcleral vessels, dehydration and severe apathy were observed. In calves with arthritis, increased joint volume, pain on palpation and lameness were observed. In animals where the owners did not authorize the surgery, treatment was instituted with sulfadoxine and flunixim meglumine. In dehydrated calves, fluid therapy was used. Animals that were surgically treated received the same clinical treatment protocol as non-operated animals. The surgical procedure was performed under general anesthesia and consisted of resection of the affected umbilical structures. Omphalophlebitis was the most common illness. The most frequent complication was sepsis. Calves treated surgically had a higher survival rate (86.66%) than those treated clinically (46.67%).Discussion: The clinical signs presented by all animals converged with the literature, allowing for clinical diagnosis. Clinical examination is essential for diagnosis in omphalitis cases. Complementary methods include ultrasound, thermography and laparoscopy, which are important to identify changes in intra-abdominal umbilical structures. Accurate diagnosis of the involved structures was only possible in animals surgically, as well as alterations in organs such as the liver and bladder. There is great variability related to the umbilical structures involved, according to initial care, breeds, seasonality or even the method of conception. Unlike what is observed in the literature, in the present study, there was a higher prevalence of omphalophlebitis, demonstrating variability in relation to the umbilical structures involved. Sepsis, observed in 16.7% of cases, results from bacterial ascension of the umbilical structures. Lameness due to polyarthritis was found in 10% of animals. Meningoencephalitis was observed in 3.3%. Hepatic and retroperitoneal abscedation were observed in 6.7% and 3.3% of cases, respectively. Conservative treatment with antibiotics and local antiseptics has a limited effect on this type of condition, which was proven in the presentstudy, since the survival rate was statistically higher in animalssurgically treated.Keywords: surgery, umbilical structures, bovine, neonate.Descritores: cirurgia, estruturas umbilicais, bovinos, neonato.Título: Surgical Approach in Calves with Omphalitis

Influence of Glenoid Labral Bumper Height and Capsular Volume on Clinical Outcomes After Arthroscopic Bankart Repair as Assessed With Serial CT Arthrogram: Can Anterior-Inferior Volume Fraction Be a Prognostic Factor?

Background: Arthroscopic labral repair combined with capsular plication decreases joint volume and restores glenoid labral bumper height; thus, the procedure helps decrease capsular redundancy. However, the decreased volume and restored glenoid labral bumper height could change over time, which could influence the outcome of the operation. Purpose: To (1) measure glenoid labral bumper height and capsular volume quantitatively in serial computed tomography arthrography (CTA) and evaluate the relationship between bumper height and joint volume and (2) compare the difference in bumper height and joint volume between groups with and without apprehension after arthroscopic Bankart repair. Study Design: Case-control study; Level of evidence, 3. Methods: Patients who had undergone arthroscopic Bankart repair between January 2012 and June 2016, and were assessed by CTA 3 to 6 months and 12 to 18 months after the operation were included. An image reconstruction program (3-dimensional slicer) was used to calculate inferior, anterior-inferior, and posterior-inferior joint volumes; the ratio of the anterior-inferior volume to the inferior volume was defined as the anterior-inferior volume fraction (VFAI). We also measured glenoid labral bumper height at the 5-, 4-, and 3-o’clock positions. Results: A total of 50 patients were enrolled as study participants (mean age, 25.2 ± 9.29 years). Of these, 10 patients had either redislocation or apprehension, and 40 patients had neither. A significant correlation was observed between 5-o’clock glenoid labral bumper height and VFAI on early CTA (3-6 months) and late CTA (12-18 months) (early CTA: Pearson coefficient, –0.335, P = .040; late CTA: Pearson coefficient, –0.468, P = .003). VFAI at the early CTA was 42.20 ± 10.15 in the group with apprehension and 33.49 ± 9.66 in the group without apprehension; a significant difference was observed. VFAI at the late CTA was 45.84 ± 11.97 in the group with apprehension and 37.65 ± 9.70 in the group without apprehension and thus showed a significant difference between the 2 groups. However, the 3-, 4-, and 5-o’clock glenoid labral bumper heights on early and late CTAs did not show a statistically significant difference between the 2 groups. Conclusion: Early postoperative VFAI is related to postoperative apprehension and redislocation and might be reduced by increasing the 5-o’clock glenoid labral bumper height.

How Will the Emerging Plurality of Lives Change How We Conceive of and Relate to Life?

The project “A Plurality of Lives” was funded and hosted by the Pufendorf Institute for Advanced Studies at Lund University, Sweden. The aim of the project was to better understand how a second origin of life, either in the form of a discovery of extraterrestrial life, life developed in a laboratory, or machines equipped with abilities previously only ascribed to living beings, will change how we understand and relate to life. Because of the inherently interdisciplinary nature of the project aim, the project took an interdisciplinary approach with a research group made up of 12 senior researchers representing 12 different disciplines. The project resulted in a joint volume, an international symposium, several new projects, and a network of researchers in the field, all continuing to communicate about and advance the aim of the project.