potassium octatitanate fibers
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2019 ◽  
Vol 93 (4) ◽  
pp. 909-920 ◽  
Author(s):  
Mohamed Abdelgied ◽  
Ahmed M. El-Gazzar ◽  
David B. Alexander ◽  
William T. Alexander ◽  
Takamasa Numano ◽  
...  

2018 ◽  
Vol 295 ◽  
pp. S205
Author(s):  
M.A.M. Abdelgied ◽  
A. El-Gazzar ◽  
D. Alexander ◽  
W. Alexander ◽  
T. Numano ◽  
...  

2018 ◽  
Vol 109 (7) ◽  
pp. 2164-2177 ◽  
Author(s):  
Mohamed Abdelgied ◽  
Ahmed M. El-Gazzar ◽  
David B. Alexander ◽  
William T. Alexander ◽  
Takamasa Numano ◽  
...  

2016 ◽  
Vol 107 (7) ◽  
pp. 1047-1054 ◽  
Author(s):  
Masanao Yokohira ◽  
Yuko Nakano‐Narusawa ◽  
Keiko Yamakawa ◽  
Nozomi Hashimoto ◽  
Shota Yoshida ◽  
...  

2015 ◽  
Vol 34 (4) ◽  
pp. 325-335 ◽  
Author(s):  
Masanao Yokohira ◽  
Nozomi Hashimoto ◽  
Toshitaka Nakagawa ◽  
Yuko Nakano ◽  
Keiko Yamakawa ◽  
...  

The present study was conducted to examine the chronic effects of potassium octatitanate fibers (trade name TISMO; chemical formula K2O·6TiO2) on the mouse lung and thoracic cavity. This method of infusion was employed to examine the direct effects of the fibers to the pleura. In the present study, 52- and 65-week experiments were employed to examine the long-term chronic effects after infusion of fiber-shaped TISMO into the thoracic cavities of A/J mice. Following this infusion, TISMO fibers were observed in the alveoli, indicating penetration through the visceral pleura. The additional histopathological detection of TISMO fibers in the liver, spleen, kidneys, ovary, heart, bone marrow, and brain of TISMO-infused mice indicated migration of the fibers out from the thoracic cavity. Atypical mesothelial cells with severe pleural proliferation were observed, but malignant mesotheliomas were not detected. This study demonstrated that intrathoracic infusion of TISMO fiber did not cause malignant mesothelioma but did cause severe chronic inflammation and proliferation of pleural mesothelial cells.


2013 ◽  
Vol 65 (6) ◽  
pp. 925-932 ◽  
Author(s):  
Masanao Yokohira ◽  
Yuko Nakano ◽  
Keiko Yamakawa ◽  
Sosuke Kishi ◽  
Fumiko Ninomiya ◽  
...  

2010 ◽  
Vol 1 (4) ◽  
pp. 589-594 ◽  
Author(s):  
MASANAO YOKOHIRA ◽  
NOZOMI HASHIMOTO ◽  
KEIKO YAMAKAWA ◽  
SATOSHI SUZUKI ◽  
KOUSUKE SAOO ◽  
...  

2004 ◽  
Vol 16 (5) ◽  
pp. 291-310 ◽  
Author(s):  
T. Ikegami ◽  
A. K. Tanaka ◽  
M. Taniguchi ◽  
M. L. Clark ◽  
H. A. Ragan ◽  
...  

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