induce phase separation
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scholarly journals Nuclear body phase separation drives telomere clustering in ALT cancer cells

2020 ◽  
Vol 31 (18) ◽  
pp. 2048-2056 ◽  
Author(s):  
Huaiying Zhang ◽  
Rongwei Zhao ◽  
Jason Tones ◽  
Michel Liu ◽  
Robert L. Dilley ◽  
...  
Keyword(s):  
Dna Repair ◽  
Phase Separation ◽  
Cancer Cells ◽  
Nuclear Body ◽  
Promyelocytic Leukemia ◽  
Nuclear Bodies ◽  
Telomere Elongation ◽  
Alternative Lengthening ◽  
Induce Phase Separation ◽  
Induce Phase

A chemical dimerization approach is developed to induce phase separation of APB nuclear bodies involved in telomere elongation in alternative lengthening of telomeres (ALT) cancer cells. It reveals that ALT telomere-associated promyelocytic leukemia nuclear body (APB) fusion leads to telomere clustering to provide templates for homology-directed telomere synthesis, an ability that is decoupled from APB function in enriching DNA repair factors.

Does dynamic vulcanization induce phase separation?

Soft Matter ◽  
2014 ◽  
Vol 10 (30) ◽  
pp. 5550-5558 ◽  
Author(s):  
Mohammad Mahdi Abolhasani ◽  
Fatemeh Zarejousheghani ◽  
Minoo Naebe ◽  
Qipeng Guo
Keyword(s):  
Phase Separation ◽  
Crosslink Density ◽  
Vinylidene Fluoride ◽  
Dynamic Vulcanization ◽  
Miscible Blends ◽  
Poly Vinylidene Fluoride ◽  
Induce Phase Separation ◽  
Induce Phase

Immiscible and miscible blends of poly(vinylidene fluoride) (PVDF) and acrylic rubber (ACM) were subjected to dynamic vulcanization to investigate the effect of crosslink density on phase separation.

Oxidized phospholipids induce phase separation in lipid vesicles

FEBS Letters ◽  
2005 ◽  
Vol 579 (21) ◽  
pp. 4577-4584 ◽  
Author(s):  
Francesco M. Megli ◽  
Luciana Russo ◽  
Karen Sabatini
Keyword(s):  
Phase Separation ◽  
Lipid Vesicles ◽  
Oxidized Phospholipids ◽  
Induce Phase Separation ◽  
Induce Phase

Temperature Gradients Induce Phase Separation in a Miscible Polymer Solution

1996 ◽  
Vol 77 (10) ◽  
pp. 1990-1993 ◽  
Author(s):  
Jiro Kumaki ◽  
Takeji Hashimoto ◽  
Steve Granick
Keyword(s):  
Phase Separation ◽  
Polymer Solution ◽  
Temperature Gradients ◽  
Induce Phase Separation ◽  
Induce Phase
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