Large-scale resculpting of cortical circuits in children after surgical resection

Despite the relative successes in the surgical treatment of pharmacoresistant epilepsy, there is rather little research on the neural (re)organization that potentially subserves behavioral compensation. Here, we examined the post-surgical functional connectivity (FC) in children and adolescents who have undergone unilateral cortical resection and, yet, display remarkably normal behavior. Conventionally, FC has been investigated in terms of the mean correlation of the BOLD time courses extracted from different brain regions. Here, we demonstrated the value of segregating the voxel-wise relationships into mutually exclusive populations that were either positively or negatively correlated. While, relative to controls, the positive correlations were largely normal, negative correlations among networks were increased. Together, our results point to reorganization in the contralesional hemisphere, possibly suggesting competition for cortical territory due to the demand for representation of function. Conceivably, the ubiquitous negative correlations enable the differentiation of function in the reduced cortical volume following a unilateral resection.

Escape behavior in gravid and non-gravid females of Gonatodes albogularis (Squamata: Sphaerodactylidae)

Escape behavior in gravid and non-gravid females of Gonatodes albogularis (Squamata: Sphaerodactylidae). Theoretical models of predator-prey relationships describe tradeoffs between energetic and other costs of escape, effectiveness of escape behavior, and predation risk. These models predict that an animal will fee when the expected ftness cost due to risk of predation becomes equal to the the cost of the escape or post-encounter ftness is maximized, depending on the model. In this framework, several individual and ecological variables have been shown to affect escape patterns, but the effect of reproductive status has been studied in few species. We assess differences in escape behavior between gravid and non-gravid females of Gonatodes albogularis. Lizards were surveyed by applying a free search method along independent transects. For each lizard, we determined reproductive status as gravid or non-gravid and recorded several variables related to escape behavior. We made a discriminant function analysis to see whether the state of individuals affect escape behavior. Our results show that the escape variables distance fed, the fnal distance and the distance to refuge differ between gravid and non-gravid females. These fndings support predictions based on risk and cost, but do not support models of fight initiation distance. Such differences could be related to a physiological process known as behavioral compensation, through which some individuals (gravid females in our case) modify their behavior to offset predation risk. Further studies are needed to see if behavioral compensation can be explained in terms of adaptive processes in G. albogularis.

Behavioral Compensation Before and After Eating at the Minnesota State Fair

People regulate their eating behavior in many ways. They may respond to overeating by compensating with healthy eating behavior or increased exercise (i.e., a sensible tradeoff), or by continuing to eat poorly (i.e., disinhibition). Conversely, people may respond to a healthy eating event by subsequently eating poorly (i.e., self-licensing) or by continuing to eat healthily (i.e., promotion spillover). We propose that people may also change their behaviors in anticipation of an unhealthy eating event, a phenomenon that we will refer to as pre-compensation. Using a survey of 430 attendees of the Minnesota State Fair over two years, we explored whether, when, and how people compensated before and after this tempting eating event. We found evidence that people use both pre-compensatory and post-compensatory strategies, with a preference for changing their eating (rather than exercise) behavior. There was no evidence that people who pre-compensated were more likely to self-license by indulging in a greater number of foods or calories at the fair than those who did not. Finally, people who pre-compensated were more likely to also post-compensate. These results suggest that changing eating or exercise behavior before exposure to a situation with many tempting foods may be a successful strategy for enjoying oneself without excessively overeating.