eg5 inhibitor
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Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor

2021 ◽  
Author(s):  
Dirk Trauner ◽  
Anna Impastato ◽  
Andrej Shemet ◽  
Nynke Veprek ◽  
Gadiel Saper ◽  
...  
Keyword(s):  
Optical Control ◽  
Eg5 Inhibitor

Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor

2021 ◽  
Author(s):  
Dirk Trauner ◽  
Anna Impastato ◽  
Andrej Shemet ◽  
Nynke Veprek ◽  
Gadiel Saper ◽  
...  
Keyword(s):  
Optical Control ◽  
Eg5 Inhibitor

scholarly journals Analyzing the Three States Inhibitory Activity of Photochromic Kinesin EG5 Inhibitor SPSAB

2021 ◽  
Vol 120 (3) ◽  
pp. 165a
Author(s):  
Islam Md Alrazi ◽  
Kei Sadakane ◽  
Shinsaku Maruta
Keyword(s):  
Inhibitory Activity ◽  
Kinesin Eg5 ◽  
Eg5 Inhibitor

scholarly journals Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5–Inhibitor Complexes

2019 ◽  
Vol 18 (12) ◽  
pp. 2394-2406 ◽  
Author(s):  
Rose-Laure Indorato ◽  
Sandeep K. Talapatra ◽  
Fangzhu Lin ◽  
Shozeb Haider ◽  
Simon P. Mackay ◽  
...  
Keyword(s):  
Eg5 Inhibitor ◽  
Clinical Candidate

Growth arrest and apoptosis induced by kinesin Eg5 inhibitor K858 and by its 1,3,4-thiadiazoline analogue in tumor cells

2018 ◽  
Vol 29 (7) ◽  
pp. 674-681 ◽  
Author(s):  
Sabrina Giantulli ◽  
Francesca De Iuliis ◽  
Ludovica Taglieri ◽  
Simone Carradori ◽  
Giusi Menichelli ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Growth Arrest ◽  
Kinesin Eg5 ◽  
Eg5 Inhibitor

scholarly journals S‑trityl‑L‑cysteine, a novel Eg5 inhibitor, is a potent chemotherapeutic strategy in neuroblastoma

2018 ◽  
Author(s):  
Wei Wu ◽  
Shao Jingbo ◽  
Weijue Xu ◽  
Jiangbin Liu ◽  
Yiming Huang ◽  
...  
Keyword(s):  
Eg5 Inhibitor

The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells

2017 ◽  
Vol 36 (1) ◽  
pp. 28-35 ◽  
Author(s):  
Ludovica Taglieri ◽  
Giovanna Rubinacci ◽  
Anna Giuffrida ◽  
Simone Carradori ◽  
Susanna Scarpa
Keyword(s):  
Glioblastoma Cells ◽  
Invasive Phenotype ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cells ◽  
Kinesin Eg5 ◽  
Eg5 Inhibitor

scholarly journals Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation

Oncotarget ◽  
2017 ◽  
Vol 8 (26) ◽  
pp. 42510-42524 ◽  
Author(s):  
Yufei Wang ◽  
Xingyu Wu ◽  
Mufeng Du ◽  
Xi Chen ◽  
Xianling Ning ◽  
...  
Keyword(s):  
Mitotic Arrest ◽  
Tumor Proliferation ◽  
Eg5 Inhibitor

Two Phase 1 dose-escalation studies exploring multiple regimens of litronesib (LY2523355), an Eg5 inhibitor, in patients with advanced cancer

2017 ◽  
Vol 79 (2) ◽  
pp. 315-326 ◽  
Author(s):  
Jeffrey R. Infante ◽  
Amita Patnaik ◽  
Claire F. Verschraegen ◽  
Anthony J. Olszanski ◽  
Montaser Shaheen ◽  
...  
Keyword(s):  
Advanced Cancer ◽  
Dose Escalation ◽  
Phase 1 ◽  
Two Phase ◽  
Eg5 Inhibitor

scholarly journals The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells

2016 ◽  
Vol 34 (4) ◽  
pp. 399-406 ◽  
Author(s):  
Francesca De Iuliis ◽  
Ludovica Taglieri ◽  
Gerardo Salerno ◽  
Anna Giuffrida ◽  
Bernardina Milana ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Kinesin Eg5 ◽  
Eg5 Inhibitor
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