chs 828
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367 POSTER Characterization of cellular resistance mechanisms towards NAD synthesis inhibitors APO866 and CHS-828

2008 ◽  
Vol 6 (12) ◽  
pp. 116
Author(s):  
U.H. Olesen ◽  
M.K. Christensen ◽  
F. Björkling ◽  
P.B. Jensen ◽  
M. Sehested ◽  
...  
Keyword(s):  
Resistance Mechanisms ◽  
Cellular Resistance ◽  
Chs 828 ◽  
Nad Synthesis

Anticancer agent CHS-828 inhibits cellular synthesis of NAD

2008 ◽  
Vol 367 (4) ◽  
pp. 799-804 ◽  
Author(s):  
Uffe Høgh Olesen ◽  
Mette Knak Christensen ◽  
Fredrik Björkling ◽  
Marja Jäättelä ◽  
Peter Buhl Jensen ◽  
...  
Keyword(s):  
Anticancer Agent ◽  
Chs 828

Pharmacokinetic–pharmacodynamic modelling of the schedule-dependent effect of the anti-cancer agent CHS 828 in a rat hollow fibre model

2005 ◽  
Vol 25 (1) ◽  
pp. 163-173 ◽  
Author(s):  
Lena E. Friberg ◽  
Saadia B. Hassan ◽  
Elin Lindhagen ◽  
Rolf Larsson ◽  
Mats O. Karlsson
Keyword(s):  
Hollow Fibre ◽  
Dependent Effect ◽  
Pharmacodynamic Modelling ◽  
Chs 828 ◽  
Anti Cancer ◽  
Cancer Agent

Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3weeks in solid tumours: An ECSG/EORTC study

2005 ◽  
Vol 41 (5) ◽  
pp. 702-707 ◽  
Author(s):  
Alain Ravaud ◽  
Thomas Cerny ◽  
Catherine Terret ◽  
Jantien Wanders ◽  
Binh Nguyen Bui ◽  
...  
Keyword(s):  
Single Dose ◽  
Phase I ◽  
Phase I Study ◽  
Solid Tumours ◽  
Chs 828

Antitumoural Effects of the Pyridyl Cyanoguanidine CHS 828 on Three Different Types of Neuroendocrine Tumours Xenografted to Nude Mice

2005 ◽  
Vol 82 (3-4) ◽  
pp. 171-176 ◽  
Author(s):  
Viktor Johanson ◽  
Yvonne Arvidsson ◽  
Lars Kölby ◽  
Peter Bernhardt ◽  
Christina Swärd ◽  
...  
Keyword(s):  
Nude Mice ◽  
Neuroendocrine Tumours ◽  
Chs 828 ◽  
Different Types

Synthesis of tritium labelled CHS 828 and its prodrug EB 1627

2005 ◽  
Vol 48 (11) ◽  
pp. 789-795 ◽  
Author(s):  
Søren Christian Schou ◽  
Charlotte Schou Hunneche ◽  
Ernst Binderup ◽  
Gunnar Grue-Sørensen
Keyword(s):  
Chs 828
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